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Gene Expression Data
Assay Details
Assay
Reference: J:262420 Szenker-Ravi E, et al., RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018 May;557(7706):564-569
Assay type: RNA in situ
MGI Accession ID: MGI:7596253
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Probe: Mm-Lgr5 (312171)
Probe preparation: Antisense DNA
Visualized with: Chromogenic
Results
Specimen 2h Lgr5/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr5; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr5/Rspo2 (upper) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr5/Rspo2 (upper)
Specimen 2h Lgr5/Rspo2 l(ower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr5; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: forelimb epidermis Absent 2h Lgr5/Rspo2 (lower) No expression in overlying ectoderm.
TS22: forelimb mesenchyme Present 2h Lgr5/Rspo2 (lower)
Specimen ED5f Lgr5/Rspo2 (upper): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr5; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung epithelium Weak ED5f Lgr5/Rspo2 (upper) Low levels expression in epithelium.
Specimen ED5f Lgr5/Rspo2 (lower): embryonic day 14.5 (more )
Note: Double labeled: blue - Lgr5; pink - Rspo2 (assay MGI:7596266).
Structure Level Pattern Image Note
TS22: lung epithelium Weak ED5f Lgr5/Rspo2 (lower) Low levels expression in epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory