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Gene Expression Data
Assay Details
Assay
Reference: J:173396 Sang L, et al., Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7596127
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6H +/- (left): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2+ (more )
Note: Double labeled: red - Pax6; green - Foxa2 (assay MGI:7596122).
Structure Level Pattern Image Note
TS15: future spinal cord Present 6H FoxA2/Pax6 +/-
Specimen 6H -/- (left): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2tm1.1Reit (more )
Note: Double labeled: red - Pax6; green - Foxa2 (assay MGI:7596122).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 6H FoxA2/Pax6 -/- Expression is ventrally expanded compared to wild type.
Specimen 6H +/+ (left-middle): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2+ (more )
Note: Double labeled: red - Pax6; green - Nkx2-2 (assay MGI:7596123).
Structure Level Pattern Image Note
TS15: future spinal cord Present 6H Nkx2.2/Pax6 +/-
Specimen 6H -/- (left-middle): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2tm1.1Reit (more )
Note: Double labeled: red - Pax6; green - Nkx2-2 (assay MGI:7596123).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 6H Nkx2.2/Pax6 -/- Expression is ventrally expanded compared to wild type.
Specimen 6H +/- (middle-right): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2+ (more )
Note: Double labeled: red - Pax6; green - Isl1 (assay MGI:7596124) and Isl2 (assay MGI:7596125).
Structure Level Pattern Image Note
TS15: future spinal cord Present 6H Isl1/2/Pax6 +/-
Specimen 6H -/- (middle-right): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2tm1.1Reit (more )
Note: Double labeled: red - Pax6; green - Isl1 (assay MGI:7596124) and Isl2 (assay MGI:7596125).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 6H Isl1/2/Pax6 -/- Expression is ventrally expanded compared to wild type.
Specimen 6H +/+ (right): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2+ (more )
Note: Double labeled: red - Pax6; green - Pax3 (assay MGI:7596126).
Structure Level Pattern Image Note
TS15: future spinal cord Present 6H Pax3/Pax6 +/-
Specimen 6H -/- (right): embryonic day 9.5; Tctn2tm1.1Reit/Tctn2tm1.1Reit (more )
Note: Double labeled: red - Pax6; green - Pax3 (assay MGI:7596126).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 6H Pax3/Pax6 -/- pExpression is ventrally expanded compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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