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Gene Expression Data
Assay Details
Assay
Reference: J:146220 Maclean G, et al., Genetic disruption of CYP26B1 severely affects development of neural crest derived head structures, but does not compromise hindbrain patterning. Dev Dyn. 2009 Mar;238(3):732-45
Assay type: RNA in situ
MGI Accession ID: MGI:7595648
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: Crabp1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6I: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch migratory neural crest cell Present Regionally restricted 6I Expression was detected in anterior second branchial arch.
TS15: face migratory cranial neural crest cell Present Regionally restricted 6I Expression was detected in migratory and early-post migratory neural crest cells at all craniofacial levels.
TS15: migrating neural crest Present Regionally restricted 6I Expression was detected in streams of cells connecting the post-otic hindbrain to the arches.

Specimen 6J: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch migratory neural crest cell Present Regionally restricted 6J Expression was detected in anterior second branchial arch.
TS15: face migratory cranial neural crest cell Present Regionally restricted 6J Expression was detected in migratory and early-post migratory neural crest cells at all craniofacial levels.
TS15: migrating neural crest Present Regionally restricted 6J Expression was detected in streams of cells connecting the post-otic hindbrain to the arches.

Specimen 6K: embryonic day 9.5; Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch migratory neural crest cell Present Regionally restricted 6K No difference in expression was observed between Cyp26b1-/- and wild type embryos.
TS15: face migratory neural crest cell Present Regionally restricted 6K No difference in expression was observed between Cyp26b1-/- and wild type embryos.
TS15: migrating neural crest Present Regionally restricted 6K The streams of cells connecting the post-otic hindbrain to the arches were highly disorganized in Cyp26b1-/- compared with wild type.

Specimen 6L: embryonic day 9.5; Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk (more )
Structure Cell Type Level Pattern Image Note
TS15: 2nd branchial arch migratory neural crest cell Present Regionally restricted 6L No difference in expression was observed between Cyp26b1-/- and wild type embryos.
TS15: face migratory neural crest cell Present Regionally restricted 6L No difference in expression was observed between Cyp26b1-/- and wild type embryos.
TS15: migrating neural crest Present Regionally restricted 6L The streams of cells connecting the post-otic hindbrain to the arches were highly disorganized in Cyp26b1-/- compared with wild type.

Specimen not shown wild type: embryonic day 8.5-9.0 (more )
Structure Cell Type Level Pattern Image Note
TS13: neural crest migratory neural crest cell Present Regionally restricted Expression was detected in migratory streams from r2 and r4.

Specimen not shown Cyp26b1-/-: embryonic day 8.5-9.0; Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk (more )
Structure Cell Type Level Pattern Image Note
TS13: neural crest migratory neural crest cell Present Regionally restricted No difference in migratory stream expression from r2 and r4 was observed between Cyp26b1-/- and wild type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory