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Gene Expression Data
Assay Details
Assay
Reference: J:220849 Achilleos A, et al., MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development. Hum Mol Genet. 2015 May 15;24(10):2884-98
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7593919
Gene symbol: Fn1
Gene name: fibronectin 1
Antibody: F-3648
Detection system: Secondary antibody coupled to Alexa Fluor 350
Results
Specimen 7A,A inset: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Present Regionally restricted 7A Expression localized to medial interface of non-segmented pre-somitic mesoderm and neural tube.
TS17: paraxial mesenchyme Present Regionally restricted 7A , 7A inset Expression in extracellular matrix surrounding each formed somite.

Specimen 7B,B inset: embryonic day 10.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col1a1-cre)1Bek/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Weak 7B Expression considerably reduced in pre-somitic mesoderm
TS17: paraxial mesenchyme Weak Regionally restricted 7B inset , 7B Expression reduced in extracellular matrix surrounding each somite/


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory