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Gene Expression Data
Assay Details
Assay
Reference: J:220849 Achilleos A, et al., MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development. Hum Mol Genet. 2015 May 15;24(10):2884-98
Assay type: RNA in situ
MGI Accession ID: MGI:7593901
Gene symbol: Uncx
Gene name: UNC homeobox
Probe: Uncx4.1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Strong Regionally restricted 5A Strong segmental expression in caudal regions of each newly formed and maturing somtites.
Specimen 5B: embryonic day 11.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col1a1-cre)1Bek/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: somite Present Regionally restricted 5B Segmental pattern of expression is perturbed. Irregular and indistinguishable somite boundaries, and abnormally spaced and fused somites.
Specimen 5D: embryonic day 10.5 (more )
Note: Double labeled: blue - Uncx and Fgf8.
Structure Level Pattern Image Note
TS17: somite Strong Regionally restricted 5D Strong segmental expression in caudal regions of each newly formed and maturing somtites.
Specimen 5F: embryonic day 10.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col1a1-cre)1Bek/0 (more )
Note: Conditional mutant. Double labeled: blue - Uncx and Fgf8.
Structure Level Pattern Image Note
TS17: somite Present Regionally restricted 5F Authors indicate a general disorganization of somites, including loss of somite polarity.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory