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Gene Expression Data
Assay Details
Assay
Reference: J:237223 Torii H, et al., Septin7 regulates inner ear formation at an early developmental stage. Dev Biol. 2016 Nov 15;419(2):217-228
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7582031
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-myosin6
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6B/C: embryonic day 18.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: green - Myo6; red - Sox2 (assay MGI:7582026).
Structure Cell Type Level Pattern Image Note
TS26: inner ear epithelium ear hair cell Present 6B , 6C
Specimen 6G/H: embryonic day 18.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: green - Myo6; red - Sox2 (assay MGI:7582026).
Structure Cell Type Level Pattern Image Note
TS26: inner ear epithelium ear hair cell Present Single cells 6H , 6G Small numbers of positive cells were seen, even though the gross morphology of the inner ears was highly hypoplastic.
Specimen 9I/K: embryonic day 18.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: green - Myo6; red - Sox2 (assay MGI:7582026).
Structure Cell Type Level Pattern Image Note
TS26: inner ear epithelium ear hair cell Present 9K , 9I
Specimen 9J/L: embryonic day 18.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: green - Myo6; red - Sox2 (assay MGI:7582026).
Structure Cell Type Level Pattern Image Note
TS26: inner ear epithelium ear hair cell Present 9J , 9L Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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