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Gene Expression Data
Assay Details
Assay
Reference: J:306325 Wang Y, et al., Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation. Front Cell Dev Biol. 2021;9:623394
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7580409
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: GB13030-2
Results
Specimen 3B Nsun5+/+: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: outflow tract Present Regionally restricted 3B Nsun5+/+ Expression was detected in proliferating cells.
Specimen 3B Nsun5+/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5+ (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: outflow tract Present Regionally restricted 3B Nsun5+/- Significantly reduced proliferation was observed.
Specimen 3B Nsun5-/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5em1Lgch (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: outflow tract Present Regionally restricted 3B Nsun5-/- Significantly reduced proliferation was observed.
Specimen 3C Nsun5+/+: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: interventricular septum Present Regionally restricted 3C Nsun5+/+ Expression was detected in proliferating cells.
Specimen 3C Nsun5+/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5+ (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: interventricular septum Present Regionally restricted 3C Nsun5+/- Significantly reduced proliferation was observed.
Specimen 3C Nsun5-/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5em1Lgch (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: interventricular septum Present Regionally restricted 3C Nsun5-/- Significantly reduced proliferation was observed.
Specimen S6b Nsun5+/+: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: compact myocardium Present Regionally restricted S6B Nsun5+/+ Expression was detected in proliferating cells in the myocardial wall.
Specimen S6b Nsun5+/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5+ (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: compact myocardium Present Regionally restricted S6B Nsun5+/- Reduced numbers of immunopositive cells were observed in the myocardial wall of E14.5 Nsun5+/- hearts.
Specimen S6b Nsun5-/-: embryonic day 14.5; Nsun5em1Lgch/Nsun5em1Lgch (more )
Note: Double labeled: green - Mki67; red - Tnnt2 (assay MGI:7580410).
Structure Level Pattern Image Note
TS22: compact myocardium Present Regionally restricted S6B Nsun5-/- Reduced numbers of immunopositive cells were observed in the myocardial wall of E14.5 Nsun5-/- hearts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory