Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242842
Kharfallah F, et al., Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization. Hum Mol Genet. 2017 Jun 15;26(12):2307-2320
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7579154
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Gene symbol:
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Tjp1
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Gene name:
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tight junction protein 1
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Results
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Specimen
1G:
embryonic day 9.0-9.5
(more  )
Specimen
1G:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.0-9.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: neural tube |
Present |
Regionally restricted |
1G (upper)
,
1G (lower)
,
1G (middle)
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Expression at cell-cell contacts.
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Specimen
1H:
(close )
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Genetic Background:
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involves: C57BL/6J * NMRI
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Mutant Allele(s):
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ScribCrc/ScribCrc
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Age:
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embryonic day 9.0-9.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: neural tube |
Present |
Regionally restricted |
1H (middle)
,
1H (lower)
,
1H (upper)
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Expression at apical side of neuroepithelial cells facing lumen of neural tube significantly reduced compared to wild type.
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Specimen
S1G:
embryonic day 11.5
(more )
Specimen
S1G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural tube |
Present |
Regionally restricted |
S1G (upper)
,
S1G (lower)
,
S1G (middle)
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Expression at cell-cell contacts.
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Specimen
S1H:
(close )
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Genetic Background:
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involves: C57BL/6J * NMRI
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Mutant Allele(s):
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ScribCrc/ScribCrc
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural tube |
Present |
Regionally restricted |
S1H (upper)
,
S1H (lower)
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S1H (middle)
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Expression significantly reduced at apical site compared to wild type.
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Analysis Tools
