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Gene Expression Data
Assay Details
Assay
Reference: J:229317 Zhu XJ, et al., Ectodermal Wnt controls nasal pit morphogenesis through modulation of the BMP/FGF/JNK signaling axis. Dev Dyn. 2016 Mar;245(3):414-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7578825
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 4F Wt: embryonic day 10.5 (more )
Note: Wild type or Gpr177(fx/+)Foxg1-Cre littermates.
Structure Level Pattern Image Note
TS17: face mesenchyme Present 4F Sox2 Wt , 4F Sox2 Wt higher mag Expression was detected in nasal pit mesenchyme.
TS17: nasal pit epithelium Present 4F Sox2 Wt , 4F Sox2 Wt higher mag
Specimen 4F Gpr177Foxg1-Cre: embryonic day 10.5; Foxg1tm1(cre)Skm/Foxg1+, Wlstm1.1Whsu/Wlstm1.1Whsu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: face mesenchyme Weak 4F Sox2 Gpr177Foxg1-Cre higher mag , 4F Sox2 Gpr177Foxg1-Cre Few immunopositive cells were observed in the mutant nasal pit mesenchyme.
TS17: nasal pit epithelium Present 4F Sox2 Gpr177Foxg1-Cre , 4F Sox2 Gpr177Foxg1-Cre higher mag
Specimen 4G: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: red - Sox2; green - Beta-gal.
Structure Level Pattern Image Note
TS15: face mesenchyme Present 4G Sox2 , 4G Merge bottom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory