Cdh1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:131173 Liu Y, et al., Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7572954
Gene symbol:	Cdh1
Gene name:	cadherin 1

Antibody:	anti-E-cadherin
Detection system:	Secondary antibody coupled to Cy3

Results

1B ©

Specimen 1B: embryonic day 16.5 (more

)

Structure	Level	Image
TS24: nasal epithelium	Present	1B
TS24: palate epithelium	Present	1B
TS24: tongue epithelium	Present	1B
TS24: nasal mesenchyme	Absent	1B
TS24: palate mesenchyme	Absent	1B
TS24: tongue mesenchyme	Absent	1B

1D ©

Specimen 1D: embryonic day 16.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Image	Note
TS24: nasal epithelium	Present	1D
TS24: palate epithelium	Present	1D
TS24: tongue epithelium	Present	1D
TS24: nasal mesenchyme	Present	1D	Expressed ectopically.
TS24: palate mesenchyme	Present	1D	Expressed ectopically.

2C ©

Specimen 2C: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: skin	Present		2C
TS23: perichondrium	Absent		2C

2I ©

Specimen 2I: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Image	Note
TS23: skin	Present		2I
TS23: perichondrium	Present		2I	Ectopically expressed.

3B ©

Specimen 3B: embryonic day 16.5 (more

)

Structure	Level	Image
TS24: cornea epithelium	Present	3B
TS24: eyelid epithelium	Present	3B
TS24: lens epithelium	Present	3B
TS24: eye muscle	Absent	3B
TS24: optic nerve	Absent	3B
TS24: retina	Absent	3B

3E ©

Specimen 3E: embryonic day 16.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Image	Note
TS24: eye muscle	Present	3E	Ectopic expression.
TS24: optic nerve	Present	3E	Ectopic expression.
TS24: retina	Present	3E	Ectopic expression.

4E ©

Specimen 4E: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: telencephalon ventricular layer	Absent		4E

4F ©

Specimen 4F: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Image	Note
TS23: telencephalon ventricular layer	Present	Regionally restricted	4F	Ectopic expression in the ventricular zone of the lateral ventricle.

4G ©

Specimen 4G: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Image	Note
TS23: telencephalon ventricular layer	Present	Regionally restricted	4G	Ectopic expression in the ventricular zone of the lateral ventricle.

4H ©

Specimen 4H: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Image	Note
TS23: diencephalon ventricular layer	Present	Regionally restricted	4H	Ectopic expression in the ventricular zone of the third ventricle.

S2A ©

Specimen S2A: embryonic day 16.5 (more

)

Structure	Level	Image
TS24: nasal epithelium	Present	S2A
TS24: palate epithelium	Present	S2A
TS24: tongue epithelium	Present	S2A
TS24: nasal mesenchyme	Absent	S2A
TS24: palate mesenchyme	Absent	S2A
TS24: tongue mesenchyme	Absent	S2A

S2B ©

Specimen S2B: embryonic day 16.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Image	Note
TS24: nasal epithelium	Present	S2B
TS24: palate epithelium	Present	S2B
TS24: tongue epithelium	Present	S2B
TS24: nasal mesenchyme	Present	S2B	Expressed ectopically.
TS24: palate mesenchyme	Present	S2B	Expressed ectopically.
TS24: tongue mesenchyme	Absent	S2B	Expression did not expand to mesenchyme in the tongue.

S3A ©

Specimen S3A: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: brain	Absent		S3A

S3B ©

Specimen S3B: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Image	Note
TS23: olfactory lobe	Present		S3B	Ectopically expressed in the mutant.

Specimen not shown: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: brain	Absent

Specimen not shown: embryonic day 15.5; Zeb1^tm2Yhi/Zeb1^tm2Yhi (more

)

Structure	Level	Pattern	Note
TS23: telencephalon ventricular layer	Present	Regionally restricted	Ectopically expressed in the proliferative regions of the telencephalic vesicle.
TS23: hypothalamus	Present	Regionally restricted	Ectopically expressed in the proliferative regions.
TS23: thalamus	Present	Regionally restricted	Ectopically expressed in the proliferative regions.

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