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Gene Expression Data
Assay Details
Assay
Reference: J:308476 Le Rolle M, et al., Arrest of WNT/beta-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2023376118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572825
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Results
Specimen 7A Control: embryonic day 13.5 (more )
Note: Double labeled: green - Lef1; red - Cdh1 (assay MGI:7572824).
Structure Level Pattern Image Note
TS21: germ cell of ovary Present 7A lower Control , 7A lower Control inset
Specimen 7A Gsk3b-/-: embryonic day 13.5; Gsk3btm1Jrw/Gsk3btm1Jrw (more )
Note: Double labeled: green - Lef1; red - Cdh1 (assay MGI:7572824).
Structure Level Pattern Image Note
TS21: germ cell of ovary Strong 7A lower Gsk3b-/- inset , 7A lower Gsk3b-/- Strong expression compared to control.
Specimen S7A Control: embryonic day 13.5 (more )
Note: Double labeled: green - Lef1; red - Cdh1 (assay MGI:7572824).
Structure Level Pattern Image Note
TS21: germ cell of ovary Present S7A lower Control MERGE , S7A lower Control LEF1
Specimen S7A Gsk3b-/-: embryonic day 13.5; Gsk3btm1Jrw/Gsk3btm1Jrw (more )
Note: Double labeled: green - Lef1; red - Cdh1 (assay MGI:7572824).
Structure Level Pattern Image Note
TS21: germ cell of ovary Strong S7A lower Gsk3b-/- LEF1 , S7A lower Gsk3b-/- MERGE Strong expression compared to control.
Specimen S8A 11.5 dpc: embryonic day 11.5 (more )
Note: Triple labeled: green - Lef1; red - Dazl (assay MGI:7572827); white - Fut4 (assay MGI:7572828).
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Strong Regionally restricted S8A 11.5 dpc MERGE , S8A 11.5 dpc LEF4 Strong expression in nucleus of germ cells.
Specimen S8A 12.5 dpc: embryonic day 12.5 (more )
Note: Triple labeled: green - Lef1; red - Dazl (assay MGI:7572827); white - Fut4 (assay MGI:7572828).
Structure Level Pattern Image Note
TS20: germ cell of ovary Strong Regionally restricted S8A 12.5 dpc MERGE , S8A 12.5 dpc LEF4 Strong expression in nucleus of germ cells.
Specimen S8A 13.5 dpc: embryonic day 13.5 (more )
Note: Triple labeled: green - Lef1; red - Dazl (assay MGI:7572827); white - Fut4 (assay MGI:7572828).
Structure Level Pattern Image Note
TS21: germ cell of ovary Strong Regionally restricted S8A 13.5 dpc LEF4 , S8A 13.5 dpc MERGE Strong expression in nucleus of germ cells.
Specimen S8A 14.5 dpc: embryonic day 14.5 (more )
Note: Triple labeled: green - Lef1; red - Dazl (assay MGI:7572827); white - Fut4 (assay MGI:7572828).
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted S8A 14.5 dpc LEF4 , S8A 14.5 dpc MERGE Expression down-regulated at 14.5 dpc.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory