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Gene Expression Data
Assay Details
Assay
Reference: J:308476 Le Rolle M, et al., Arrest of WNT/beta-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2023376118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572819
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Results
Specimen 5A 12.5 dpc: embryonic day 12.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS20: germ cell of ovary Present Regionally restricted 5A 12.5 dpc betaCATENIN , 5A 12.5 dpc MERGE Expression in the nucleus of gonocytes.
Specimen 5A 14.5 dpc: embryonic day 14.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted 5A 14.5 dpc MERGE , 5A 14.5 dpc betaCATENIN Expression mostly localized to cytoplasm.
Specimen 5B 12.5 dpc: embryonic day 12.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS20: germ cell of ovary Present Regionally restricted 5B 12.5 dpc betaCATENIN , 5B 12.5 dpc MERGE Expression in the nucleus of gonocytes.
Specimen 5B 14.5 dpc: embryonic day 14.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted 5B 14.5 dpc betaCATENIN , 5B 14.5 dpc MERGE Expression mostly localized to cytoplasm.
Specimen S8B 11.5 dpc: embryonic day 11.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS19: gonad Strong Regionally restricted S8B 11.5 dpc betaCATENIN , S8B 11.5 dpc MERGE Strong expression in nucleus, cytoplasm and membrane of both somatic cells and germ cells.
Specimen S8B 12.5 dpc: embryonic day 12.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS20: germ cell of ovary Strong Regionally restricted S8B 12.5 dpc betaCATENIN , S8B 12.5 dpc MERGE Strong expression in nucleus, cytoplasm and membrane of germ cells.
TS20: ovary Strong Regionally restricted S8B 12.5 dpc MERGE , S8B 12.5 dpc betaCATENIN Strong expression in nucleus, cytoplasm and membrane of somatic cells.
Specimen S8B 13.5 dpc: embryonic day 13.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS21: germ cell of ovary Present Regionally restricted S8B 13.5 dpc MERGE , S8B 13.5 dpc betaCATENIN Expression slightly decreased at 13.5 dpc.
Specimen S8B 14.5 dpc: embryonic day 14.5 (more )
Note: Double labeled: green - Ctnnb1; red - Pou5f1 (assay MGI:7572817).
Structure Level Pattern Image Note
TS22: germ cell of ovary Present Regionally restricted S8B 14.5 dpc MERGE , S8B 14.5 dpc betaCATENIN Expression located in cytoplasm and at cell membrane at 14.5 dpc
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory