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Gene Expression Data
Assay Details
Assay
Reference: J:281210 Krejci J, et al., Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli. Stem Cells Int. 2017;2017:1021240
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572550
Gene symbol: Coil
Gene name: coilin
Antibody: coilin Antibody (H-300): sc-32860
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1a: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 1a Expressed in Cajal bodies at the cortex periphery.

Specimen 1b/c: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 1b , 1c Expressed in Cajal bodies at the cortex periphery. In approximately 90% of the cell nuclei at the cortex periphery, the Cajal bodies were located away from clusters of centromeric heterochromatin called chromocenters.

Specimen 2a: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lateral ventricle choroid plexus Strong 2a The cells in this region did not have easily discernable Cajal bodies.

Specimen 2b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Clusters 2b Expressed inside the cell nuclei occupying the cortex periphery.

Specimen 2d/e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 2 cont'd_e , 2d Expressed in crescent-like accumulation and individual canonical Cajal bodies.

Specimen 2f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 2 cont'd_f Expressed in crescent-like accumulation and individual canonical Cajal bodies.

Specimen 3bA: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Strong 3bA

Specimen 3bB/C/D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Strong 3bD , 3bC , 3bB Expressed in the highly DAPI-dense nuclear regions surrounding single Cajal bodies.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory