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Gene Expression Data
Assay Details
Assay
Reference: J:203998 Luxey M, et al., Eph:ephrin-B1 forward signaling controls fasciculation of sensory and motor axons. Dev Biol. 2013 Nov 15;383(2):264-74
Assay type: RNA in situ
MGI Accession ID: MGI:7571343
Gene symbol: Efnb1
Gene name: ephrin B1
Probe: ephrin-B1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Strong Regionally restricted 1A Expression throughout limb mesenchyme. Higher expression at distal tip and in a ventral region.
TS20: dorsal root ganglion Present 1A
TS20: axial mesoderm Weak Regionally restricted 1A Weakly expressed in axial mesenchyme surrounding spinal cord.
TS20: spinal cord ventral horn Absent 1A
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb bud Present Graded 1D Expression throughout limb mesenchyme in a proximo-distal gradient.
TS17: future spinal cord Present Regionally restricted 1D No expression in ventral horn of spinal cord.
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb bud Present Regionally restricted 1E Expression becomes regionalized with slightly stronger ventral expression.
TS19: neural tube basal columns Absent 1E No expression in ventral horn of spinal cord.
Specimen 5A: embryonic day 12.5; Efnb1tm1Sor/Efnb1+ (more )
Structure Level Pattern Image Note
TS20: forelimb Present 5A
Specimen 5B: embryonic day 12.5; Efnb1tm1Sor/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Absent 5B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory