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Gene Expression Data
Assay Details
Assay
Reference: J:187602 Al Alam D, et al., FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. Dev Biol. 2012 Sep 15;369(2):340-8
Assay type: RNA in situ
MGI Accession ID: MGI:7571240
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 12.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: cecum Strong Regionally restricted 1A Strong expression in both epithelium and mesenchyme of cecum.
TS20: small intestine epithelium Present 1A Expression restricted to epithelium of small intestine.
TS20: large intestine Present Regionally restricted 1A Expression absent in colon.
Specimen 1B: embryonic day 13.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS21: cecum Strong Regionally restricted 1B Strong expression in both epithelium and mesenchyme of cecum.
TS21: small intestine epithelium Present 1B Expression restricted to epithelium of small intestine.
TS21: large intestine Present Regionally restricted 1B Expression absent in colon.
Specimen 1C: embryonic day 14.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS22: cecum Strong Regionally restricted 1C Strong expression in both epithelium and mesenchyme of cecum.
TS22: small intestine epithelium Present 1C Expression restricted to epithelium of small intestine.
TS22: large intestine Present Regionally restricted 1C Expression absent in colon.
Specimen 1D: embryonic day 12.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: cecum Present Regionally restricted 1D Expression in both epithelium and mesenchyme of cecum.
Specimen 1E: embryonic day 13.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS21: cecum Present Regionally restricted 1E Expression in both epithelium and mesenchyme of cecum.
Specimen 1F: embryonic day 14.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS22: cecum Present Regionally restricted 1F Expression in both epithelium and mesenchyme of cecum.
Specimen 1G: embryonic day 12.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS20: small intestine epithelium Present Regionally restricted 1G Expression in epithelium at E12.5.
Specimen 1H: embryonic day 13.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS21: small intestine Present 1H
Specimen 1I: embryonic day 14.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS22: small intestine epithelium Present 1I Expression in epithelium and mesenchyme at E14.5.
TS22: small intestine mesenchyme Present 1I Expression in epithelium and mesenchyme at E14.5.
Specimen 2A: embryonic day 11.5; Pitx2tm1.1Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS19: gut Present 2A
Specimen 2B: embryonic day 11.5; Pitx2tm1.1Sac/Pitx2tm1.1Sac, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: gut mesenchyme Absent 2B , 2B inset
Specimen 5E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cecum Present 5E
Specimen 5F: embryonic day 14.5; Fgf9tm1.1Fwan/Fgf9tm1.1Fwan, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cecum Present 5F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory