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Gene Expression Data
Assay Details
Assay
Reference: J:122792 Jacobs FM, et al., Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. Development. 2007 Jul;134(14):2673-84
Assay type: RNA in situ
MGI Accession ID: MGI:7571188
Gene symbol: Th
Gene name: tyrosine hydroxylase
Probe: Th probe
Probe preparation: labelled with P33
Visualized with: Autoradiography
Results
Specimen 1AA: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: substantia nigra pars compacta dopaminergic neuron Present Regionally restricted 1AA Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 1AC: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: substantia nigra pars compacta dopaminergic neuron Present Regionally restricted 1AC Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 1AE: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: ventral tegmental area dopaminergic neuron Present Regionally restricted 1AE Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 1AG: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: ventral tegmental area dopaminergic neuron Present Regionally restricted 1AG Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 1AI: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: ventral tegmental area dopaminergic neuron Present Regionally restricted 1AI Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 1AK: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: ventral tegmental area dopaminergic neuron Present Regionally restricted 1AK Expression in cell bodies of meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 2 TH Lateral: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 2_TH Lateral Expression in cell bodies of fully differentiated meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 2 TH (2nd row): embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 2_TH (2nd row) Expression in cell bodies of fully differentiated meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 2 TH (3rd row): embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 2_TH (3rd row) Expression in cell bodies of fully differentiated meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 2 TH Medial: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 2_TH Medial Expression in cell bodies of fully differentiated meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 3AA: postnatal adult; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 3AA
Specimen 3AC: postnatal adult; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 3AC
Specimen 3AE: postnatal adult; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 3AE
Specimen 3B TH L: embryonic day 13.5; Pitx3ak/Pitx3ak (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 3B TH L Expression present in cells in meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 3B TH (2nd row): embryonic day 13.5; Pitx3ak/Pitx3ak (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 3B TH (2nd row) Expression present in cells in meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 3B TH M: embryonic day 13.5; Pitx3ak/Pitx3ak (more )
Structure Cell Type Level Pattern Image Note
TS21: midbrain dopaminergic neuron Present Regionally restricted 3B TH M Expression present in cells in meso-diencephalic dopaminergic (mdDA) neurons.
Specimen 4B TH (upper): postnatal adult (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 4B TH (upper)
Specimen 4B TH (lower): postnatal adult; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 4B TH (lower) Expression not altered compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory