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Gene Expression Data
Assay Details
Assay
Reference: J:171473 Nie X, et al., Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. Dev Biol. 2011 Apr 1;352(1):141-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567870
Gene symbol: Smad9
Gene name: SMAD family member 9
Antibody: anti-phospho-Smad-1/5/8
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein. The specificity of the antibody used was not detailed; all family members have been annotated.
Results
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present 4C
TS17: ureteric bud Present 4C
TS17: urinary system mesenchyme Present 4C
Specimen 4D: embryonic day 10.5; Six1tm1Mair/Six1tm1Mair (more )
Structure Level Pattern Image Note
TS17: ureteric bud Present 4D
TS17: urinary system mesenchyme Present 4D
TS17: metanephric mesenchyme Present 4D Percentage of positive cells vs total number of cells was comparable between the wild-type and the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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