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Gene Expression Data
Assay Details
Assay
Reference: J:311540 Oliver BL, et al., Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7547373
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2 (AF2018)
Detection system: Secondary antibody
Results
Specimen 1A: postnatal day 1 (more )
Note: Triple labeled: blue - Sox2; green - Myo7a (assay MGI:7547372); red - phalloidin.
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 1A Expression is seen in the sensory domain.
Specimen 5A: embryonic day 12.5 (more )
Note: Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS20: cochlear duct Present Regionally restricted 5A Expression is seen in the prosensory domain.
Specimen 5B: embryonic day 13.5 (more )
Note: Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS21: cochlear duct Present Regionally restricted 5B Expression is seen in the prosensory domain.
Specimen 5C: embryonic day 14.5 (more )
Note: base t1. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 5C Expression is seen in the prosensory domain.
Specimen 5D: embryonic day 14.5 (more )
Note: mid t2. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 5D Expression is seen in the prosensory domain.
Specimen 5E: embryonic day 14.5 (more )
Note: apex t3. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 5E Expression is seen in the prosensory domain.
Specimen 6A: embryonic day 16.5 (more )
Note: base t1. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 6A Expression is seen in the prosensory domain.
Specimen 6B: embryonic day 16.5 (more )
Note: mid t2. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 6B Expression is seen in the prosensory domain.
Specimen 6B': embryonic day 16.5 (more )
Note: mid t2. Triple labeled: red - Sox2; green - Porcn (assay MGI:7547384); blue - DAPI.
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 6B' Expression is seen in the prosensory domain.
Specimen 6C: embryonic day 16.5 (more )
Note: mid t3. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 6C Expression is seen in the prosensory domain.
Specimen 6D: embryonic day 16.5 (more )
Note: apex t4. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 6D Expression is seen in the prosensory domain.
Specimen 6E: postnatal day 1 (more )
Note: base t1. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6E Expression is seen in the prosensory domain.
Specimen 6F: postnatal day 1 (more )
Note: mid t2. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6F Expression is seen in the prosensory domain.
Specimen 6F': postnatal day 1 (more )
Note: mid t2. Triple labeled: red - Sox2; green - Porcn (assay MGI:7547384); blue - DAPI.
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6F' Expression is seen in the prosensory domain.
Specimen 6G: postnatal day 1 (more )
Note: mid t3. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6G Expression is seen in the prosensory domain.
Specimen 6H: postnatal day 1 (more )
Note: apex t4. Double labeled: magenta - Sox2; green - Porcn (assay MGI:7547384).
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 6H Expression is seen in the prosensory domain.
Specimen 7C: embryonic day 14.5 (more )
Note: Control. Triple labeled: red - Sox2; green - Gsk3b (assay MGI:7547392); blue - DAPI.
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted 7C Expression is seen in the prosensory domain.
Specimen 7D: embryonic day 14.5; Gsk3btm2Jrw/Gsk3btm2Jrw, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant. Triple labeled: red - Sox2; green - Gsk3b (assay MGI:7547392); blue - DAPI.
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted 7D Expression is seen in the prosensory domain; this region is slightly expanded in the mutant relative to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory