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Gene Expression Data
Assay Details
Assay
Reference: J:329220 Chen Y, et al., Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1alpha-glycolysis axis. Cell Death Dis. 2022 Sep 20;13(9):803
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7546917
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 [EPR14335-78] (ab185966)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen S1A Sox9: embryonic day 13.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present S1A Sox9

Specimen S1B Sox9: embryonic day 15.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS23: humerus Present S1B Sox9

Specimen S1C Sox9: embryonic day 18.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS26: humerus Present S1C Sox9

Specimen 2A WT: embryonic day 18.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS26: long bone epiphyseal plate proliferative zone Present 2A WT
TS26: long bone epiphyseal plate resting zone Present 2A WT

Specimen 2A CKO: embryonic day 18.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya, Tg(Col2a1-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: long bone epiphyseal plate proliferative zone Weak 2A CKO Ratio of expressing cells decreased compared with wild type.
TS26: long bone epiphyseal plate resting zone Weak 2A CKO Ratio of expressing cells decreased compared with wild type.
TS26: tibia Present Regionally restricted 2A CKO No expression in atypical chondrocytes.

Specimen S2C WT: embryonic day 15.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS23: tibia Present S2C WT

Specimen S2C CKO: embryonic day 15.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya, Tg(Col2a1-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: tibia Present S2C CKO No significant difference compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory