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Gene Expression Data
Assay Details
Assay
Reference: J:341686 Mehanna S, et al., Beclin1 is essential for the pancreas development. Dev Biol. 2023 Sep 21;504:113-119
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7545017
Gene symbol: Ins2
Gene name: insulin II
Antibody: anti-Insulin
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1D Becn1f/f: postnatal day 0; Becn1tm1a(KOMP)Wtsi/Becn1tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS27: pancreas Present 1D Becn1f/f
Specimen 1D Becn1f/f;PtfaCre/+: postnatal day 0; Becn1tm1a(KOMP)Wtsi/Becn1tm1a(KOMP)Wtsi, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pancreas Trace Regionally restricted 1D Becn1f/f;Ptf1aCre/+ Slight appearance of insulin-positive cells within pancreatic interstitial tissues.
Specimen 4D Becn1f/f: postnatal week 3; Becn1tm1a(KOMP)Wtsi/Becn1tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: pancreas Present 4D Becn1f/f
Specimen 4D Becn1f/f;PtfaCre/+: postnatal week 3; Becn1tm1a(KOMP)Wtsi/Becn1tm1a(KOMP)Wtsi, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pancreas Weak 4D Becn1;Ptf1aCre/+ Decreased number pf expressing cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory