Gene Expression Data
Assay Details
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Assay
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Reference:
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J:341657
Park J, et al., Msx1 Heterozygosity in Mice Enhances Susceptibility to Phenytoin-Induced Hypoxic Stress Causing Cleft Palate. Cleft Palate Craniofac J. 2021 Jun;58(6):697-706
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7544990
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Gene symbol:
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Msx1
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Gene name:
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msh homeobox 1
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Probe:
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Msx1 cDNA2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
S2A:
embryonic day 11.5
(more  )
Specimen
S2A:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: axial skeleton |
Present |
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S2A
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Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
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| TS19: face |
Present |
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S2A
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Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
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| TS19: forelimb bud |
Present |
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S2A
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Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
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| TS19: hindlimb bud |
Present |
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S2A
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Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
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| TS19: otocyst |
Present |
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S2A
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Expression in face, otic vesicle, forelimb, hindlimb and vertebral column.
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Specimen
S2C:
embryonic day 11.5
(more )
Specimen
S2C:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: latero-nasal process |
Present |
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S2C
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Expression in medial and lateral nasal processes, and maxillary and mandibular processes.
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| TS19: mandibular process |
Present |
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S2C
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Expression in medial and lateral nasal processes, and maxillary and mandibular processes.
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| TS19: maxillary process |
Present |
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S2C
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Expression in medial and lateral nasal processes, and maxillary and mandibular processes.
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| TS19: medial-nasal process |
Present |
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S2C
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Expression in medial and lateral nasal processes, and maxillary and mandibular processes.
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Specimen
S2D:
embryonic day 11.5
(more )
Specimen
S2D:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S2E:
embryonic day 12.5
(more )
Specimen
S2E:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: maxillary process |
Strong |
Regionally restricted |
S2E
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Intense expression in anterior palatal process.
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Specimen
S2F:
embryonic day 12.5
(more )
Specimen
S2F:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: palatal shelf |
Strong |
Regionally restricted |
S2F
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Intense expression in anterior part of developing palate.
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Specimen
6A/B:
embryonic day 13.5
(more )
Specimen
6A/B:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: maxillary process |
Present |
Regionally restricted |
6B
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6A
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Expression in anterior palatal process, but slightly weaker compared to E12.
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Specimen
6E/F:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Msx1tm1b(KOMP)Wtsi/Msx1+
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: maxillary process |
Present |
Regionally restricted |
6E
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6F
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Expression slightly downregulated in anterior palatal process compared to wild type.
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Specimen
S3A/B:
embryonic day 12.5
(more )
Specimen
S3A/B:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
S3C/D:
embryonic day 13.5
(more )
Specimen
S3C/D:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools