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Gene Expression Data
Assay Details
Assay
Reference: J:186504 Tanimoto Y, et al., Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2). J Biol Chem. 2012 Jun 15;287(25):21429-38
Assay type: RNA in situ
MGI Accession ID: MGI:7543944
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2-I cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 2E Expressed in the osteogenic front.
TS23: inter-parietal bone primordium Present Regionally restricted 2E Expressed in the osteogenic front.
TS23: parietal bone Present Regionally restricted 2E Expressed in the osteogenic front.
TS23: chondrocranium Present Regionally restricted 2E Expressed in the osteogenic fronts and sutural mesenchymal cells some distance from osteogenic fronts, especially around the frontal and parietal bones.

Specimen 2F: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS23: chondrocranium Present Regionally restricted 2F Expressed in less intensity in the osteogenic front. Expression in the sutural mesenchymal cells was similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory