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Gene Expression Data
Assay Details
Assay
Reference: J:281311 Nakano Y, et al., Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7541514
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: clone CB-955 (#C9848)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S2K WT P16: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S2K WT (P16)
Specimen S2K Srrm3gt/gt P16: postnatal day 16; Srrm3Gt(IST12726F8)Tigm/Srrm3Gt(IST12726F8)Tigm (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S2K Srrm3 gt/gt (P16)
Specimen S2K WT P40: postnatal day 40 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S2K WT (P40)
Specimen S2K Srrm3gt/gt P40: postnatal day 40; Srrm3Gt(IST12726F8)Tigm/Srrm3Gt(IST12726F8)Tigm (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S2K Srrm3 gt/gt (P40)
Specimen S2L Srrm3gt/gt P40: postnatal day 40; Srrm3Gt(IST12726F8)Tigm/Srrm3Gt(IST12726F8)Tigm (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present S2L Srrm3 gt/gt (P40)
Specimen S2L Srrm3gt/gt P90: postnatal day 90; Srrm3Gt(IST12726F8)Tigm/Srrm3Gt(IST12726F8)Tigm (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Single cells S2L Srrm3 gt/gt (P90) Most Purkinjec cells degenerated in the Srrm3<gt/gt> mice between P40 and P90.
Specimen S2L WT P90: postnatal day 90 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present S2L WT (P90)
Specimen S2N WT: postnatal day 90 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present S2N WT
Specimen S2N Srrm3gt/gt P90: postnatal day 90; Srrm3Gt(IST12726F8)Tigm/Srrm3Gt(IST12726F8)Tigm (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Single cells S2N Srrm3 gt/gt Most Purkinjec cells degenerated in the Srrm3<gt/gt> mice between P40 and P90.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory