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Gene Expression Data
Assay Details
Assay
Reference: J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539743
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1 (#11-002)
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: anterior cardinal vein Present Regionally restricted 1b Expression is nuclear in endothelial cells.
TS19: lymphatic system Present Regionally restricted 1b Expression is in sprouting lymphatic endothelial cells.
Specimen 2b: embryonic day 14.5 (more )
Note: Double labeled: blue - Prox1; brown - Tek (assay MGI:7539745).
Structure Level Pattern Image Note
TS22: jugular lymph sac Very strong Regionally restricted 2b Expression is in the endothelial cells of jugular lymph sac.
TS22: lymphatic vessel endothelium Very strong Regionally restricted 2b Expression is in the endothelial cells of jugular lymph sac.
Specimen 2c: embryonic day 14.5 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS22: jugular lymph sac Very strong Regionally restricted 2c Expression is in the endothelial cells of jugular lymph sac.
TS22: lymphatic vessel endothelium Very strong Regionally restricted 2c Expression is in the endothelial cells of jugular lymph sac.
TS22: blood vessel endothelium Absent 2c
Specimen 2e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lymphatic system Very strong Regionally restricted 2e Expression is in the endothelial cells of thoracic duct.
TS22: lymphatic vessel endothelium Very strong Regionally restricted 2e Expression is in the endothelial cells of thoracic duct.
Specimen 2f: embryonic day 14.5 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS22: lymphatic system Very strong 2f Expression is in the endothelial cells of thoracic duct.
TS22: lymphatic vessel endothelium Very strong 2f Expression is in the endothelial cells of thoracic duct.
TS22: blood vessel endothelium Absent 2f
Specimen 2h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lymphatic vessel endothelium Very strong Regionally restricted 2h Expression is in the endothelial cells of lymphatic vasculature around axillary vein.
Specimen 2i: embryonic day 14.5 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS22: lymphatic vessel endothelium Very strong Regionally restricted 2i Expression is in the endothelial cells of lymphatic vasculature around axillary vein.
TS22: blood vessel endothelium Absent 2i
Specimen 3b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lymphatic vessel endothelium Present Regionally restricted 3b Expression is in lymphatic endothelial cells around bronchus and pulmonary artery.
Specimen 3f: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lymphatic vessel endothelium Very strong 3f
Specimen 3g: embryonic day 16.5 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS24: lymphatic vessel endothelium Very strong 3g
Specimen 3i: embryonic day 16.5 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS24: lymphatic vessel endothelium Very strong 3i
Specimen 5b: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lymph node Very strong Regionally restricted 5b Expression is in endothelial cells of marginal and medullary sinuses.
TS27: blood vessel Absent 5b
Specimen 5c: postnatal day 3 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS27: lymph node Very strong Regionally restricted 5c Expression is in endothelial cells of marginal and medullary sinuses.
TS27: blood vessel Absent 5c
Specimen 5e: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: lymphatic vessel endothelium Very strong Regionally restricted 5e Expression is in endothelial cells of lymphatic vasculature in the lung.
Specimen 5f: postnatal day 3 (more )
Note: Double labeled: blue - Prox1; brown - Pecam1 (assay MGI:7539750).
Structure Level Pattern Image Note
TS27: lymphatic vessel endothelium Very strong Regionally restricted 5f Expression is in endothelial cells of lymphatic vasculature in the lung.
Specimen 6b: postnatal day 7 (more )
Note: Double labeled: blue - Prox1; brown - Angpt2 (assay MGI:7539711).
Structure Level Pattern Image Note
TS28: lymphatic system Present Regionally restricted 6b Expression is in the jugular lymph sac and small lymphatics.
Specimen 6c: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: lymphatic system Present Regionally restricted 6c Expression is in the jugular lymph sac and small lymphatics.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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