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Gene Expression Data
Assay Details
Assay
Reference: J:116501 Fukami M, et al., CXorf6 is a causative gene for hypospadias. Nat Genet. 2006 Dec;38(12):1369-71
Assay type: RNA in situ
MGI Accession ID: MGI:7539148
Gene symbol: Mamld1
Gene name: mastermind-like domain containing 1
Probe: G630014P10Rik cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2a E11.5 testis: embryonic day 11.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS19: gonad Weak Regionally restricted 2a E11.5 Testis Expressed in the internal region.
Specimen 2a E11.5 ovary: embryonic day 11.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted 2a E11.5 Ovary Expressed in a small number of somatic cells, primarily at the boundary to the mesonephros.
Specimen 2a E12.5 testis: embryonic day 12.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Cell Type Level Pattern Image Note
TS20: testis Present 2a E12.5 Testis
TS20: Sertoli cell Sertoli cell Present 2a E12.5 Testis inset
TS20: Leydig cell Leydig cell Present Single cells 2a E12.5 Testis Expressed in a small number of cells.
Specimen 2a E12.5 ovary: embryonic day 12.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS20: ovary Present Regionally restricted 2a E12.5 Ovary Expressed in a small number of somatic cells, primarily at the boundary to the mesonephros.
Specimen 2a E14.5 testis: embryonic day 14.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 2a E14.5 Testis
TS22: Leydig cell Leydig cell Present 2a E14.5 Testis , 2a E14.5 Testis inset Expressed in the majority of cells.
Specimen 2a E14.5 ovary: embryonic day 14.5 (more )
Note: Double labeled: blue - Mamld1; brown - Nr5a1 (assay MGI:7539149).
Structure Level Pattern Image Note
TS22: ovary Weak Regionally restricted 2a E14.5 Ovary Expressed in a small number of somatic cells in the internal region.
TS22: paramesonephric duct of female Present 2a E14.5 Ovary
Specimen 2b birth testis: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: seminiferous cord Trace 2b birth Testis
Specimen 2b birth ovary: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: ovary Absent 2b birth Ovary
Specimen 2b 1w testis: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Weak 2b 1w Testis
Specimen 2b 1w ovary: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: ovary Absent 2b 1w Ovary
Specimen 2b 2w testis: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 2w Testis
Specimen 2b 2w ovary: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Trace 2b 2w Ovary
Specimen 2b 3w testis: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 3w Testis
Specimen 2b 3w ovary: postnatal week 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Present Regionally restricted 2b 3w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
TS28: ovary mature follicle granulosa cell Present Regionally restricted 2b 3w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
Specimen 2b 8w testis: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: seminiferous cord Trace 2b 8w Testis
Specimen 2b 8w ovary: postnatal week 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: ovary follicle cell granulosa cell Present Regionally restricted 2b 8w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
TS28: ovary mature follicle granulosa cell Present Regionally restricted 2b 8w Ovary Expressed in granulosa cells at the perifollicular regions of most of Graafian follicles.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: external genitalia Weak Expressed at a level similar to that detected in the neighboring extragenital tissues.
TS20: male external genitalia Weak Diffuse
TS20: adrenal primordium Absent
TS20: forebrain Present
TS20: pancreas Present
TS20: paramesonephric duct Present
TS20: somite Present
TS20: spinal cord Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory