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Gene Expression Data
Assay Details
Assay
Reference: J:336094 Zheng H, et al., CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7532577
Gene symbol: Dmp1
Gene name: dentin matrix protein 1
Antibody: Anti-DMP1 (A16832)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 4I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: molar Weak 4I

Specimen 4J: embryonic day 16.5; Stub1tm1Cpat/Stub1tm1Cpat (more )
Structure Level Pattern Image Note
TS24: molar Weak 4J Expression in the mutant was comparable to the wild type.

Specimen 4K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: molar Present 4K

Specimen 4L: embryonic day 18.5; Stub1tm1Cpat/Stub1tm1Cpat (more )
Structure Level Pattern Image Note
TS26: molar Present 4L Expression in the mutant was comparable to the wild type.

Specimen 4M: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: molar ameloblast Present 4M
TS27: molar odontoblast Present 4M

Specimen 4N: postnatal day 1; Stub1tm1Cpat/Stub1tm1Cpat (more )
Structure Cell Type Level Pattern Image Note
TS27: molar odontoblast Present Regionally restricted 4N Differentiating odontoblasts had higher expression in the mutant compared with wild type.
TS27: molar ameloblast Present 4N Expression was increased in the mutant ameloblasts compared with wild type.

Specimen S1B: postnatal day 2 (more )
Structure Cell Type Level Pattern Image Note
TS27: incisor mesenchyme mesenchymal cell Weak Regionally restricted S1B' , S1B Weak expression was detected in undifferentiated dental mesenchymal cells.
TS27: incisor odontoblast Strong S1B''' , S1B' , S1B'' , S1B
TS27: incisor preodontoblast Strong S1B''' , S1B' , S1B'' , S1B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory