Gene Expression Data
Assay Details
Assay
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Reference:
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J:336094
Zheng H, et al., CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7532577
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Gene symbol:
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Dmp1
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Gene name:
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dentin matrix protein 1
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Antibody:
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Anti-DMP1 (A16832)
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Detection system:
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Secondary antibody coupled to Alexa Fluor 594
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Results
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Specimen
4I:
embryonic day 16.5
(more )
Specimen
4I:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4J:
(close )
Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS24: molar |
Weak |
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4J
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Expression in the mutant was comparable to the wild type.
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Specimen
4K:
embryonic day 18.5
(more )
Specimen
4K:
(close )
Genetic Background:
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Not Specified
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
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Specimen
4L:
(close )
Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
|
embryonic day 18.5
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS26: molar |
Present |
|
4L
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Expression in the mutant was comparable to the wild type.
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Specimen
4M:
postnatal day 1
(more )
Specimen
4M:
(close )
Genetic Background:
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Not Specified
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Age:
|
postnatal day 1
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4N:
(close )
Genetic Background:
|
involves: 129S/SvEv
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Mutant Allele(s):
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Stub1tm1Cpat/Stub1tm1Cpat
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Age:
|
postnatal day 1
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Paraffin
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: molar |
odontoblast |
Present |
Regionally restricted |
4N
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Differentiating odontoblasts had higher expression in the mutant compared with wild type.
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TS27: molar |
ameloblast |
Present |
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4N
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Expression was increased in the mutant ameloblasts compared with wild type.
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Specimen
S1B:
postnatal day 2
(more )
Specimen
S1B:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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