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Gene Expression Data
Assay Details
Assay
Reference: J:336094 Zheng H, et al., CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7531835
Gene symbol: Stub1
Gene name: STIP1 homology and U-Box containing protein 1
Antibody: Anti-Stub1 (ab134064) [EPR4447]
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A: postnatal day 2 (more )
Structure Cell Type Level Pattern Image Note
TS27: incisor Present Widespread 1Aa
TS27: incisor mesenchyme mesenchymal cell Strong Regionally restricted 1Aa , 1Ab Strong expression was detected in undifferentiated dental mesenchymal cells.
TS27: incisor epithelium Present Regionally restricted 1Ab , 1Aa Expression was detected in the inner enamel epithelium.
TS27: incisor preodontoblast Moderate 1Aa , 1Ac
TS27: incisor ameloblast Present 1Ac , 1Aa
TS27: incisor odontoblast Moderate 1Ad , 1Aa
Specimen 1Ba: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: molar mesenchyme mesenchymal cell Present Regionally restricted 1Ba Expression was detected in undifferentiated dental mesenchymal cells.
Specimen 1Bb: postnatal day 2 (more )
Structure Cell Type Level Pattern Image Note
TS27: molar ameloblast Present 1Bb
TS27: molar odontoblast Present 1Bb
Specimen S5B WT: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: molar Present S5B WT
Specimen S5B Chip KO: postnatal day 1; Stub1tm1Cpat/Stub1tm1Cpat (more )
Structure Level Pattern Image Note
TS27: molar Absent S5B Chip KO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory