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Gene Expression Data
Assay Details
Assay
Reference: J:268103 Dykes IM, et al., A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity. Sci Rep. 2018 Jul 11;8(1):10439
Assay type: RNA in situ
MGI Accession ID: MGI:7530984
Gene symbol: Lefty2
Gene name: left-right determination factor 2
Probe: Lefty-2 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4d: embryonic day 8.0 (more )
Note: 6-somite stage
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 4d Expressed exclusively in the left.

Specimen 4f: embryonic day 8.0; Zic2iso/Zic2iso (more )
Note: 6-somite stage
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent 4f

Specimen 4e: embryonic day 8.0 (more )
Note: 4-somite stage
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 4e Expressed exclusively in the left.

Specimen 4g: embryonic day 8.0; Zic2iso/Zic2iso (more )
Note: 4-somite stage
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent 4g

Specimen not shown WT/Het: embryonic day 8.0 (more )
Note: 4-6 somites, summarized in Fig 4h
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted Expressed exclusively in the left of embryos aged between 4 to 6 somites. Strong expression in 4 embryos, and weak in 2.

Specimen not shown WT/Het: embryonic day 8.0 (more )
Note: 1 somite, summarized in Fig 4h
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent Absent expression in one 1-somite embryo.

Specimen not shown iso/iso: embryonic day 8.0; Zic2iso/Zic2iso (more )
Note: 4-6 somites, summarized in Fig 4h
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent All mutants failed to express Lefty2.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory