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Gene Expression Data
Assay Details
Assay
Reference: J:339600 Hermosilla Aguayo V, et al., ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42
Assay type: RNA in situ
MGI Accession ID: MGI:7529470
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 9A Vps25+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present 9D +/+ top , 9D +/+ bottom
TS19: 1st branchial arch maxillary component Present 9D +/+ top , 9D +/+ bottom
TS19: latero-nasal process Present 9D +/+ top , 9D +/+ bottom
TS19: medial-nasal process Present 9D +/+ top , 9D +/+ bottom
TS19: nasal pit Present 9D +/+ top , 9D +/+ bottom
Specimen 9A Vps25ENU/ENU: embryonic day 11.5; Vps25m1Lis/Vps25m1Lis (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Weak 9D ENU/ENU bottom , 9D ENU/ENU top Expression was decreased and distribution of transcript was perturbed in the mutant compared with wild type.
TS19: nasal pit Weak 9D ENU/ENU bottom , 9D ENU/ENU top Expression was decreased and distribution of transcript was perturbed in the mutant compared with wild type.
TS19: 1st branchial arch maxillary component Weak 9D ENU/ENU bottom , 9D ENU/ENU top
TS19: latero-nasal process Weak 9D ENU/ENU bottom , 9D ENU/ENU top
TS19: medial-nasal process Weak 9D ENU/ENU bottom , 9D ENU/ENU top
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory