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Gene Expression Data
Assay Details
Assay
Reference: J:241504 Van Dyken SJ, et al., Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease. Cell. 2017 Apr 20;169(3):497-509.e13
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7528919
Gene symbol: Chia1
Gene name: chitinase, acidic 1
Reporter: tdTomato
Antibody: anti-DsRed (632496)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1: postnatal; Chia1tm1.1(icre)Lky/Chia1tm1.1(icre)Lky (more )
Note: Triple labeled: red - Chia1 reporter; green - Epcam (assay MGI:7529643); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium lung secretory cell Present 1C
Specimen S2A: postnatal; Chia1tm1.1(icre)Lky/Chia1tm1.1(icre)Lky (more )
Note: Triple labeled: red - Chia1 reporter; green - Foxj1 (assay MGI:7529650); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium Present S2A Merge , S2A ChiaRed
TS28: lung epithelium lung multiciliated epithelial cell Absent S2A Merge , S2A ChiaRed no overlap with Foxj1+ ciliated cells
Specimen S2B: postnatal; Chia1tm1.1(icre)Lky/Chia1tm1.1(icre)Lky (more )
Note: Triple labeled: red - Chia1 reporter; green - Sftpc (assay MGI:7529646); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium Present S2B ChiaRed , S2B Merge
TS28: lung epithelium pulmonary alveolar type 2 cell Present S2B ChiaRed , S2B Merge overlap with SPC+ type2 alveolar cells
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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