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Gene Expression Data
Assay Details
Assay
Reference: J:85979 Muller-Decker K, et al., Expression of cyclooxygenase isozymes during morphogenesis and cycling of pelage hair follicles in mouse skin: precocious onset of the first catagen phase and alopecia upon cyclooxygenase-2 overexpression. J Invest Dermatol. 2003 Oct;121(4):661-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526800
Gene symbol: Ptgs2
Gene name: prostaglandin-endoperoxide synthase 2
Antibody: anti-COX-2 (sc-1745)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: epidermis Present 2A Expression in epithelial precursor cells of embryonic epidermis prior to onset of epidermal stratification.

Specimen 2B: embryonic day 15.0 (more )
Structure Cell Type Level Pattern Image Note
TS23: epidermis basal layer basal cell of epidermis Present 2B
TS23: periderm Present 2B Expression in outermost ectoderm periderm layer of stratified epidermis.
TS23: epidermis Present Regionally restricted 2B No expression in differentiated layers in between.

Specimen 2C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: hair germ Present 2C Expression in elongated hair germs and hair pegs at stages 2 and 3.
TS26: hair peg Present 2C Expression in elongated hair germs and hair pegs at stages 2 and 3.
TS26: hair follicle dermal papilla Absent

Specimen 2C inset: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: hair germ Present 2C inset Expression in elongated hair germs and hair pegs at stages 2 and 3.
TS26: hair peg Present 2C inset Expression in elongated hair germs and hair pegs at stages 2 and 3.

Specimen 2D: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 2D Expression restricted to basal outer root sheath.
TS28: hair follicle Present Regionally restricted 2D Expression in outer root sheath cells of distal and also proximal hair follicles.
TS28: sebaceous gland basal cell of epidermis Present Regionally restricted 2D Expression in basal cells of sebaceous gands.

Specimen 2D inset: postnatal day 8 (more )
Structure Cell Type Level Pattern Image Note
TS28: interfollicular epidermis basal cell of epidermis Present Regionally restricted 2D inset Expression in basal interfollicular epidermis.

Specimen 2E: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 2E Expression in outer root sheath of growing hair follicles.

Specimen 2F: postnatal day 17 (more )
Structure Level Pattern Image Note
TS28: hair follicle Weak 2F Expression declined in catagen hair follicles at P17.

Specimen 2G: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hair follicle Trace 2G Expression barely detectable in telogen hair follicles at P21.

Specimen 2H: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 2H Expression in outer root sheath of late anagen hair follicles at P28.

Specimen 2H inset: postnatal day 25 (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 2H inset Re-expression in outer root sheath of early anagen hair follicles at P25.

Specimen 2I: postnatal day 28 (more )
Structure Cell Type Level Pattern Image Note
TS28: sebaceous gland basal cell of epidermis Present 2I Expression in basal cells of sebaceous gands.
TS28: interfollicular epidermis Trace 2I Expression barely detectable in interfollicular epidermis.
TS28: hair follicle Trace 2I Expression barely detected in resting hair follicles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory