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Gene Expression Data
Assay Details
Assay
Reference: J:315020 Yao G, et al., The cytoplasmic protein Pacsin 2 in kidney development and injury repair. Kidney Int. 2013 Mar;83(3):426-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526221
Gene symbol: Pacsin2
Gene name: protein kinase C and casein kinase substrate in neurons 2
Antibody: anti-Pacsin2
Results
Specimen 1a newborn: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS27: renal proximal tubule epithelial cell of proximal tubule Strong 1a upper right , 1a upper left Expressed in the apical membrane of Lotus tetragonolobus agglutinin positive proximal tubules.
Specimen not shown 1 week: postnatal week 1 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS28: renal proximal tubule epithelial cell of proximal tubule Present Expressed in the apical membrane of Lotus tetragonolobus agglutinin positive proximal tubules.
Specimen 1a 3-weeks: postnatal week 3 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS28: renal proximal tubule epithelial cell of proximal tubule Present 1a lower left , 1a lower right Remarkably reduced expression and became mostly cytoplasmic, with only weak signals on the apical membrane in a small fraction (about 5%).
Specimen 1b newborn: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS27: renal distal tubule epithelial cell of distal tubule Strong 1b upper left , 1b upper right Expressed in the apical membrane of Dolichos biflorus agglutinin positive distal tubules.
Specimen not shown 1 week: postnatal week 1 (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS28: renal distal tubule epithelial cell of distal tubule Present Expressed in the apical membrane of Dolichos biflorus agglutinin positive distal tubules.
Specimen 1b 3-weeks: postnatal week 3 (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS28: renal distal tubule epithelial cell of distal tubule Strong 1b lower right , 1b lower left Even stronger expression in the apical membrane of Dolichos biflorus agglutinin positive distal tubules.
Specimen 2a1: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Level Pattern Image Note
TS27: ureteric tip Strong 2a1 Strong apical labeling.
TS27: ureteric trunk Strong 2a1 Strong apical labeling.
TS27: renal vesicle Absent 2a1
TS27: s-shaped body Absent 2a1
TS27: early nephron Weak 2a1
Specimen 2a2/3: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Level Pattern Image Note
TS27: ureteric tip Strong 2a2 , 2a3 Strong apical labeling.
TS27: ureteric trunk Strong 2a2 , 2a3 Strong apical labeling.
TS27: renal vesicle Absent 2a3 , 2a2
Specimen 2a4/5: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Level Pattern Image Note
TS27: ureteric tip Strong 2a5 , 2a4 Strong apical labeling.
TS27: ureteric trunk Strong 2a5 , 2a4 Strong apical labeling.
TS27: s-shaped body Absent 2a4 , 2a5
Specimen 2b1/2: postnatal newborn (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Level Pattern Image Note
TS27: glomerular tuft Weak 2b1 , 2b2
TS27: parietal epithelium of mature renal corpuscle Weak 2b1 , 2b2
Specimen 2b3/4: postnatal month 3 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Level Pattern Image Note
TS28: glomerular tuft Present 2b3 , 2b4 There was a remarkable upregulation.
Specimen 7a control: postnatal month 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: renal proximal tubule epithelial cell of proximal tubule Present 7a upper left Expressed at basal levels in the cytoplasm.
Specimen 7b control: postnatal month 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: renal distal tubule epithelial cell of distal tubule Present 7b upper left
Specimen S1 E15.5 upper: embryonic day 15.5 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS23: cortical early proximal tubule epithelial cell of proximal tubule Present S1_E15.5 upper left , S1_E15.5 upper right Expressed in the apical membrane of Lotus tetragonolobus agglutinin positive proximal tubules.
Specimen S1 E15.5 lower: embryonic day 15.5 (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS23: cortical early distal tubule epithelial cell of distal tubule Present S1_E15.5 lower right , S1_E15.5 lower left Expressed in the apical membrane of Dolichos biflorus agglutinin positive distal tubules.
Specimen S1 E18.5 upper: embryonic day 18.5 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS26: renal proximal tubule epithelial cell of proximal tubule Present S1_E18.5 upper left , S1_E18.5 upper right Expressed in the apical membrane of Lotus tetragonolobus agglutinin positive proximal tubules.
Specimen S1 E18.5 lower: embryonic day 18.5 (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS26: renal distal tubule epithelial cell of distal tubule Present S1_E18.5 lower left , S1_E18.5 lower right Expressed in the apical membrane of Dolichos biflorus agglutinin positive distal tubules.
Specimen S5a control: postnatal month 3 (more )
Note: Double labeled: red - Pacsin2; green - Lotus tetragonolobus agglutinin (LTA).
Structure Cell Type Level Pattern Image Note
TS28: renal proximal tubule epithelial cell of proximal tubule Weak S5a upper left , S5a upper right
Specimen S5b control: postnatal month 3 (more )
Note: Double labeled: red - Pacsin2; green - Dolichos biflorus agglutinin (DBA).
Structure Cell Type Level Pattern Image Note
TS28: renal distal tubule epithelial cell of distal tubule Present S5b upper left , S5b upper right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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