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Gene Expression Data
Assay Details
Assay
Reference: J:132979 Potok MA, et al., WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526042
Gene symbol: Gh
Gene name: growth hormone
Antibody: anti-GH
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis Present 2K
Specimen 2L: embryonic day 16.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS24: adenohypophysis Weak 2L Slight reduction in expression compared to wild type.
Specimen 4Ba: embryonic day 18.5; Wnt4tm1Amc/Wnt4+, Wnt5atm1Amc/Wnt5a+ (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Ba
Specimen 4Bb: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 4Bb
Specimen 4Bc: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Structure Cell Type Level Pattern Image Note
TS26: adenohypophysis somatotroph Present Regionally restricted 4Bc Expression in dysmorphic region containing somatotropes remains largely unaffected.
Specimen 4Bd: embryonic day 18.5; Wnt4tm1Amc/Wnt4tm1Amc, Wnt5atm1Amc/Wnt5atm1Amc (more )
Structure Cell Type Level Pattern Image Note
TS26: adenohypophysis somatotroph Weak 4Bd Expression in somatotropes slightly reduced compared to wild type.
Specimen 5 GH +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 5_GH +/+
Specimen 5 GH -/-: embryonic day 18.5; Wnt6tm1Akis/Wnt6tm1Akis (more )
Structure Level Pattern Image Note
TS26: adenohypophysis Present 5_GH -/- Expression unchanged compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/04/2024
MGI 6.13 		The Jackson Laboratory