About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:339296 Fries M, et al., Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7525631
Gene symbol: Zic2
Gene name: zinc finger protein of the cerebellum 2
Antibody: anti-ZIC2
Results
Specimen 1I ZIC2: embryonic day 16.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Slc6a4tm1(cre)Xz/Slc6a4+ (more )
Note: Conditional mutant. Double labeled: green - Zic2; magenta - recombinase reporter.
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 1I ZIC2/TdTom , 1I ZIC2 Expression in ventrotemporal area.
Specimen 3A' Pou3f1+/- ZIC2: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Level Pattern Image Note
TS25: retina Present 3A' Pou3f1+/- ZIC2
Specimen 3A' Pou3f1-/- ZIC2: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted 3A' Pou3f1-/- ZIC2 Increase in proportion of expressing cells in retinal ganglion cell layer in central retina.
Specimen 3E Pou3f1+/-: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Level Pattern Image Note
TS25: retina Present 3E Pou3f1+/- (merged) , 3E Pou3f1+/- ZIC2
Specimen 3E Pou3f1-/-: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Level Pattern Image Note
TS25: retina Present 3E Pou3f1-/- ZIC2 , 3E Pou3f1-/- (merged) Increased in number of expressing cells compared to heterozygous embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory