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Gene Expression Data
Assay Details
Assay
Reference: J:339296 Fries M, et al., Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7525631
Gene symbol: Zic2
Gene name: zinc finger protein of the cerebellum 2
Antibody: anti-ZIC2
Results
Specimen 1I ZIC2: embryonic day 16.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Slc6a4tm1(cre)Xz/Slc6a4+ (more )
Note: Conditional mutant. Double labeled: green - Zic2; magenta - recombinase reporter.
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 1I ZIC2/TdTom , 1I ZIC2 Expression in ventrotemporal area.

Specimen 3A' Pou3f1+/- ZIC2: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Level Pattern Image Note
TS25: retina Present 3A' Pou3f1+/- ZIC2

Specimen 3A' Pou3f1-/- ZIC2: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted 3A' Pou3f1-/- ZIC2 Increase in proportion of expressing cells in retinal ganglion cell layer in central retina.

Specimen 3E Pou3f1+/-: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Level Pattern Image Note
TS25: retina Present 3E Pou3f1+/- (merged) , 3E Pou3f1+/- ZIC2

Specimen 3E Pou3f1-/-: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Level Pattern Image Note
TS25: retina Present 3E Pou3f1-/- ZIC2 , 3E Pou3f1-/- (merged) Increased in number of expressing cells compared to heterozygous embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory