Gene Expression Data
Assay Details
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Assay
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Reference:
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J:215514
Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7522070
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Gene symbol:
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Cdh8
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Gene name:
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cadherin 8
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Probe:
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Cad8 cDNA3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
7C Dmrt5+/+:
embryonic day 18.5
(more  )
Specimen
7C Dmrt5<+/+>:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: frontal cortex |
Present |
Regionally restricted |
7C Dmrt5+/+
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High expression was detected in the motor cortex region.
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Specimen
7C Dmrt5<-/->:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Dmrta2tm1Ejbd/Dmrta2tm1Ejbd
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: neocortex |
Present |
Regionally restricted |
7C Dmrt5-/-
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The high expression domain of the mutant appeared to occupy most of the reduced cortex.
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Analysis Tools
