About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: RNA in situ
MGI Accession ID: MGI:7521965
Gene symbol: Wnt8b
Gene name: wingless-type MMTV integration site family, member 8B
Probe: Wnt8b probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4D Dmrt5+/+: embryonic day 12.5 (more )
Note: Double labeled: blue - Wnt8b; brown - Lhx1 (assay MGI:7521979) and Lhx5 (assay MGI:7521980).
Structure Level Pattern Image Note
TS20: cortical hem Present 4D Dmrt5+/+
TS20: diencephalon Present Regionally restricted 4D Dmrt5+/+ Expression was detected in the eminentia thalami.
TS20: telencephalon Present Graded 4D Dmrt5+/+ High-medial to low-lateral graded expression was observed in the dorsomedial telencephalon.
Specimen 4D Dmrt5-/-: embryonic day 12.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Note: Double labeled: blue - Wnt8b; brown - Lhx1 (assay MGI:7521979) and Lhx5 (assay MGI:7521980).
Structure Level Pattern Image Note
TS20: telencephalon Weak Regionally restricted 4D Dmrt5-/- Dorsomedial telencephalon expression was strongly reduced in the mutant.
TS20: diencephalon Present Regionally restricted 4D Dmrt5-/- Eminentia thalami expression was still detected in the mutant, as shown by co-labeling with the Lhx1/5 marker.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory