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Gene Expression Data
Assay Details
Assay
Reference: J:49099 Weiner JA, et al., Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain. J Comp Neurol. 1998 Sep 7;398(4):587-98
Assay type: RNA in situ
MGI Accession ID: MGI:7520848
Gene symbol: Lpar1
Gene name: lysophosphatidic acid receptor 1
Probe: vzg-1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: brain meninges Present 1A
TS24: cerebral cortex ventricular layer Present 1A
TS24: cortical plate Absent 1A
TS24: ganglionic eminence Absent 1A
Specimen 1C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Weak 1C
TS26: brain meninges Present 1C
Specimen 1D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: brain meninges Present 1D
TS27: cerebral cortex Absent 1D
Specimen 2A: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: hindbrain Present Regionally restricted 2A Expression is in the caudal hindbrain.
Specimen 2B: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: medulla oblongata Present Regionally restricted 2B Expression is in the ventral columns.
Specimen 2C: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 2C
TS28: cerebellum external granule cell layer Absent 2C
TS28: cerebellum internal granule cell layer Absent 2C
Specimen 3A: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 3A
TS28: nerve fiber tract Present 3A
TS28: cerebral cortex Present Regionally restricted 3A Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
Specimen 3B: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 3B
TS28: nerve fiber tract Present 3B
TS28: cerebral cortex Present Regionally restricted 3B Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
Specimen 3C: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 3C
TS28: nerve fiber tract Present 3C
TS28: cerebellum granule cell layer Present Regionally restricted 3C Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
TS28: cerebellum molecular layer Present Regionally restricted 3C Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
Specimen 3D: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 3D
TS28: nerve fiber tract Present 3D
TS28: cerebellum granule cell layer Present Regionally restricted 3D Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
TS28: cerebellum molecular layer Present Regionally restricted 3D Expression is in white matter tracts and is generally absent from or sparse in neuronal regions.
Specimen 3E: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: nerve fiber tract Present 3E
TS28: hindbrain Present Regionally restricted 3E Expression is in white matter tracts.
Specimen 3F: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: nerve fiber tract Present 3F
TS28: hindbrain Present Regionally restricted 3F Expression is in white matter tracts.
Specimen 4A: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present Regionally restricted 4A Expression is in white matter tracts.
TS28: corpus callosum Present Regionally restricted 4A Expression is in white matter tracts.
TS28: nerve fiber tract Present Regionally restricted 4A Expression is in white matter tracts.
TS28: fimbria hippocampus Strong Regionally restricted 4C , 4A , 4D Expression is in white matter tracts.
TS28: cerebral internal capsule Strong Regionally restricted 4A , 4C Expression is in white matter tracts.
TS28: cerebral peduncle Strong Regionally restricted 4E , 4A Expression is in white matter tracts.
TS28: anterior commissure Strong Regionally restricted 4B , 4A Expression is in white matter tracts.
TS28: hippocampus granule cell layer Absent 4A
Specimen 6A: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Level Pattern Image Note
TS28: fimbria hippocampus Present Regionally restricted 6A Expression is in the white matter regions surrounding the unlabeled hippocampal granule neurons.
TS28: hippocampus Present Regionally restricted 6A Expression is in the white matter regions surrounding the unlabeled hippocampal granule neurons.
TS28: hippocampus granule cell layer Absent 6A
Specimen 6C: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Cell Type Level Pattern Image Note
TS28: anterior commissure oligodendrocyte Present Single cells 6C , 6E Expression is in oligodendrocytes.
Specimen 6F: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex oligodendrocyte Present Single cells 6F Expression is in oligodendrocytes.
Specimen 6H: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Cell Type Level Pattern Image Note
TS28: cerebral internal capsule oligodendrocyte Present Single cells 6H Expression is in oligodendrocytes.
Specimen 6I: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte Present Single cells 6I Expression is in oligodendrocytes.
Specimen 6J: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; red - Plp1 (assay MGI:7520859).
Structure Cell Type Level Pattern Image Note
TS28: anterior commissure oligodendrocyte Present Single cells 6J Expression is in oligodendrocytes.
Specimen 7A: postnatal day 1 (more )
Note: Double labeled: purple - Lpar1; pink - Gfap (assay MGI:7520874).
Structure Cell Type Level Pattern Image Note
TS27: forebrain meninges Present 7A
TS27: forebrain astrocyte of the forebrain Absent 7A Expression is absent in astrocytes.
Specimen 7B: postnatal day 18 (more )
Note: Double labeled: purple - Lpar1; pink - Gfap (assay MGI:7520874).
Structure Cell Type Level Pattern Image Note
TS28: fimbria hippocampus Present Regionally restricted 7B Expression is in the white matter regions.
TS28: hippocampus astrocyte Absent 7B Expression is absent in astrocytes.
Specimen Table 1 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: medulla oblongata Trace There was very light labeling that was not observed in all sections.
TS27: hindbrain Trace Regionally restricted There was very light labeling in the medulla that was not observed in all sections. Absent in pontine fibers.
TS27: anterior commissure Absent
TS27: basal ganglia Absent
TS27: cerebellum white matter Absent
TS27: cerebral cortex Absent
TS27: cerebral internal capsule Absent
TS27: corpus callosum Absent
TS27: fimbria hippocampus Absent
TS27: hypothalamus Absent
TS27: thalamus Absent
Specimen Table 1 P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: medulla oblongata Trace There was very light labeling that was not observed in all sections.
TS27: hindbrain Trace Regionally restricted There was very light labeling in the medulla that was not observed in all sections. Absent in pontine fibers. Figure 2 states there is expression is in the caudal hindbrain.
TS27: anterior commissure Absent
TS27: basal ganglia Absent
TS27: cerebellum white matter Absent
TS27: cerebral cortex Absent
TS27: cerebral internal capsule Absent
TS27: corpus callosum Absent
TS27: fimbria hippocampus Absent
TS27: hypothalamus Absent
TS27: thalamus Absent
Specimen Table 1 P6: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: medulla oblongata Weak
TS28: hindbrain Weak Regionally restricted There was light labeling in the medulla and there was very light labeling in the white matter that was not observed in all sections. Absent in pontine fibers.
TS28: cerebellum white matter Trace There was very light labeling that was not observed in all sections.
TS28: anterior commissure Absent
TS28: basal ganglia Absent
TS28: cerebral cortex Absent
TS28: cerebral internal capsule Absent
TS28: corpus callosum Absent
TS28: fimbria hippocampus Absent
TS28: hypothalamus Absent
TS28: thalamus Absent
Specimen Table 1 P9: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: medulla oblongata Present
TS28: cerebellum white matter Weak
TS28: corpus callosum Trace There was very light labeling that was not observed in all sections.
TS28: hindbrain Trace Regionally restricted There was very light labeling in pontine fibers that was not observed in all sections.
TS28: anterior commissure Absent
TS28: basal ganglia Absent
TS28: cerebral cortex Absent
TS28: cerebral internal capsule Absent
TS28: fimbria hippocampus Absent
TS28: hypothalamus Absent
TS28: thalamus Absent
Specimen Table 1 P12: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: medulla oblongata Moderate
TS28: cerebellum white matter Present
TS28: hindbrain Present Regionally restricted Expression is in pontine fibers.
TS28: basal ganglia Weak
TS28: cerebral internal capsule Weak
TS28: corpus callosum Weak
TS28: fimbria hippocampus Weak
TS28: cerebral cortex Trace Single cells There was very light labeling in scattered cells that was not observed in all sections.
TS28: hypothalamus Trace Single cells There was very light labeling in scattered cells that was not observed in all sections.
TS28: anterior commissure Absent
Specimen Table 1 P15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Strong
TS28: medulla oblongata Strong
TS28: anterior commissure Moderate
TS28: cerebral internal capsule Moderate
TS28: corpus callosum Moderate
TS28: fimbria hippocampus Moderate
TS28: hindbrain Moderate Regionally restricted Expression is in pontine fibers.
TS28: thalamus Moderate Regionally restricted Expression is moderate in the anterior thalamus and weak in the posterior thalamus.
TS28: cerebral cortex Present Single cells Expression is in scattered cells.
TS28: basal ganglia Present
TS28: hypothalamus Weak
Specimen Table 1 P18: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Strong
TS28: fimbria hippocampus Strong
TS28: medulla oblongata Strong
TS28: hindbrain Strong Regionally restricted Expression is in pontine fibers.
TS28: anterior commissure Moderate
TS28: cerebellum white matter Moderate
TS28: cerebral internal capsule Moderate
TS28: cerebral cortex Present Single cells Expression is in scattered cells.
TS28: basal ganglia Present
TS28: hypothalamus Present
TS28: thalamus Present
Specimen Table 1 P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: anterior commissure Strong
TS28: corpus callosum Strong
TS28: fimbria hippocampus Strong
TS28: medulla oblongata Strong
TS28: hindbrain Strong Regionally restricted Expression is in pontine fibers.
TS28: cerebellum white matter Moderate
TS28: cerebral internal capsule Moderate
TS28: hypothalamus Moderate
TS28: cerebral cortex Present Single cells Expression is in scattered cells.
TS28: thalamus Present Regionally restricted Expression is in the anterior thalamus and is weak in the posterior thalamus.
TS28: basal ganglia Weak
Specimen Table 1 P28: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: hindbrain Strong Regionally restricted Expression is in pontine fibers.
TS28: anterior commissure Moderate
TS28: cerebellum white matter Moderate
TS28: cerebral internal capsule Moderate
TS28: corpus callosum Moderate
TS28: fimbria hippocampus Moderate
TS28: hypothalamus Moderate
TS28: medulla oblongata Moderate
TS28: cerebral cortex Weak Single cells Expression is in scattered cells.
TS28: basal ganglia Weak
TS28: thalamus Weak Regionally restricted Expression is in the anterior thalamus and is trace in the posterior thalamus.
Specimen Table 1 Young adult: postnatal week 6-10 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present
TS28: fimbria hippocampus Weak
TS28: hindbrain Weak Regionally restricted Expression is in pontine fibers.
TS28: cerebral internal capsule Trace There was very light labeling that was not observed in all sections.
TS28: medulla oblongata Trace There was very light labeling that was not observed in all sections.
TS28: cerebral cortex Trace There was very light labeling in scattered cells that was not observed in all sections.
TS28: anterior commissure Absent
TS28: basal ganglia Absent
TS28: cerebellum white matter Absent
TS28: hypothalamus Absent
TS28: thalamus Absent
Specimen Table 1 Aged adult: postnatal adult (more )
Note: Mice were over 3 months old.
Structure Level Pattern Image Note
TS28: corpus callosum Weak
TS28: fimbria hippocampus Trace There was very light labeling that was not observed in all sections.
TS28: medulla oblongata Trace There was very light labeling that was not observed in all sections.
TS28: hindbrain Trace There was very light labeling in pontine fibers that was not observed in all sections.
TS28: anterior commissure Absent
TS28: basal ganglia Absent
TS28: cerebellum white matter Absent
TS28: cerebral cortex Absent
TS28: cerebral internal capsule Absent
TS28: hypothalamus Absent
TS28: thalamus Absent
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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