Isl1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:224892 Yan Y, et al., Prdx4 is a compartment-specific H2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2. Nat Commun. 2015;6:7006
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7520254
Gene symbol:	Isl1
Gene name:	ISL1 transcription factor, LIM/homeodomain

Antibody:	anti-Isl1/2
Detection system:	Secondary antibody
Assay notes:	The specificity of the antibody used was not detailed; both family members have been annotated.

Results

S3c ©

Specimen S3c +/y: embryonic day 13.5 (more

)
Note: Double labeled: red - Isl1 and Isl2; green - Lhx1 (assay MGI:7520153).

Structure	Cell Type	Level	Pattern	Image	Note
TS21: spinal cord ventral horn	spinal cord motor neuron	Present		S3c

S3f ©

Specimen S3f -y or -/-: embryonic day 13.5; Prdx4^tm1.1Jufu/? (more

)
Note: The sex of the specimen was not specified. Double labeled: red - Isl1 and Isl2; green - Lhx1 (assay MGI:7520153).

Structure	Cell Type	Level	Pattern	Image	Note
TS21: spinal cord ventral horn	spinal cord motor neuron	Present		S3f	Late-born lateral division of lateral motor column (LMCm, Isl2+Lhx1+) motor neurons were decreased, compared with the wild-type littermates.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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