Gene Expression Data
Assay Details
Assay
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Reference:
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J:87736
Gazit R, et al., Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development. 2004 Feb;131(4):903-13
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7518851
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Gene symbol:
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Atoh1
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Gene name:
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atonal bHLH transcription factor 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1A:
embryonic day 14.5; Atoh1tm2Hzo/Atoh1 +
(more )
Specimen
1A:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Atoh1tm2Hzo/Atoh1+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: rhombic lip |
cerebellar granule cell precursor |
Present |
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1A
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Expression in cerebellar granule cell (CGC) precursors occupying rhombic lip.
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Specimen
1B:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Atoh1tm2Hzo/Atoh1tm2Hzo
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: rhombic lip |
cerebellar granule cell precursor |
Present |
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1B
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Expression similar to that of heterozygous. Rhombic lip seemed smaller compared to heterozygote.
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Specimen
1C:
embryonic day 14.5; Atoh1tm2Hzo/Atoh1 +
(more )
Specimen
1C:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Atoh1tm2Hzo/Atoh1+
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: rhombic lip |
cerebellar granule cell precursor |
Present |
|
1C
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Expression in cerebellar granule cell (CGC) precursors occupying rhombic lip.
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Specimen
1D:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
|
Atoh1tm2Hzo/Atoh1tm2Hzo
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Age:
|
embryonic day 14.5
|
Sex:
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Not Specified
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Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: rhombic lip |
cerebellar granule cell precursor |
Present |
|
1D
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Expression similar to that of heterozygous. Rhombic lip seemed smaller compared to heterozygote.
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Specimen
1E:
embryonic day 16.5; Atoh1tm2Hzo/Atoh1 +
(more )
Specimen
1E:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
|
Atoh1tm2Hzo/Atoh1+
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Age:
|
embryonic day 16.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: rhombic lip |
Present |
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1E
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TS24: cerebellum |
Present |
Regionally restricted |
1E
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Expression in cerebellar granule cell (CGC) precursors migrating over surface of cerebellum to generate EGL.
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Specimen
1F:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Atoh1tm2Hzo/Atoh1tm2Hzo
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Age:
|
embryonic day 16.5
|
Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: rhombic lip |
|
Present |
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1F
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TS24: cerebellum |
cerebellar granule cell precursor |
Present |
Regionally restricted |
1F
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Less expressing cells at cerebellar surface.
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Specimen
1G:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Atoh1tm2Hzo/Atoh1tm2Hzo
|
Age:
|
embryonic day 14.5
|
Sex:
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Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: rhombic lip |
cerebellar granule cell precursor |
Present |
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1G
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