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Gene Expression Data
Assay Details
Assay
Reference: J:87736 Gazit R, et al., Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development. 2004 Feb;131(4):903-13
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7518851
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 14.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Cell Type Level Pattern Image Note
TS22: rhombic lip cerebellar granule cell precursor Present 1A Expression in cerebellar granule cell (CGC) precursors occupying rhombic lip.

Specimen 1B: embryonic day 14.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Cell Type Level Pattern Image Note
TS22: rhombic lip cerebellar granule cell precursor Present 1B Expression similar to that of heterozygous. Rhombic lip seemed smaller compared to heterozygote.

Specimen 1C: embryonic day 14.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Cell Type Level Pattern Image Note
TS22: rhombic lip cerebellar granule cell precursor Present 1C Expression in cerebellar granule cell (CGC) precursors occupying rhombic lip.

Specimen 1D: embryonic day 14.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Cell Type Level Pattern Image Note
TS22: rhombic lip cerebellar granule cell precursor Present 1D Expression similar to that of heterozygous. Rhombic lip seemed smaller compared to heterozygote.

Specimen 1E: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Level Pattern Image Note
TS24: rhombic lip Present 1E
TS24: cerebellum Present Regionally restricted 1E Expression in cerebellar granule cell (CGC) precursors migrating over surface of cerebellum to generate EGL.

Specimen 1F: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Cell Type Level Pattern Image Note
TS24: rhombic lip Present 1F
TS24: cerebellum cerebellar granule cell precursor Present Regionally restricted 1F Less expressing cells at cerebellar surface.

Specimen 1G: embryonic day 14.5; Atoh1tm2Hzo/Atoh1tm2Hzo (more )
Structure Cell Type Level Pattern Image Note
TS22: rhombic lip cerebellar granule cell precursor Present 1G


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory