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Gene Expression Data
Assay Details
Assay
Reference: J:162064 Abe M, et al., Hand2 regulates chondrogenesis in vitro and in vivo. Bone. 2010 May;46(5):1359-68
Assay type: RNA in situ
MGI Accession ID: MGI:7518545
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: dhand probe16
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Strong Non-Uniform 1A Expression is weak in the anterior and strong in the posterior limb mesenchyme.
TS19: future arm mesenchyme Strong Regionally restricted 1A Expression is in the region closely juxtaposing the aggregating chondrocytes of the zeugopod and is weak or absent within the site of chondrogenesis.
TS19: handplate mesenchyme Strong Regionally restricted 1A Expression is in the region closely juxtaposing the aggregating chondrocytes of the autopod and is weak or absent within the site of chondrogenesis.

Specimen 1C: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 1C , 1E Expression is in the region surrounding the forming digit anlagen.
TS20: hand pre-cartilage condensation chondrocyte Absent 1E , 1C Expression is absent in chondrocytes.

Specimen 6C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forelimb cartilage condensation Absent 6C

Specimen S4E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forelimb cartilage condensation Absent S4E

Specimen S5B: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: forearm mesenchyme chondrocyte Present Regionally restricted S5B Expression is in the prehypertrophic and hypertrophic chondrocytes and is not or only weakly detected in the resting and proliferating chondrocytes.
TS24: forearm mesenchyme hypertrophic chondrocyte Present Regionally restricted S5B Expression is in the prehypertrophic and hypertrophic chondrocytes and is not or only weakly detected in the resting and proliferating chondrocytes.
TS24: forearm bone Present S5B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory