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Gene Expression Data
Assay Details
Assay
Reference: J:338879 Hernandez-Garcia A, et al., SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2. Hum Mol Genet. 2023 Jun 19;32(13):2152-2161
Assay type: RNA in situ
MGI Accession ID: MGI:7518250
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: Wnt4 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3C,C': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: atrioventricular canal endocardial lining Present Regionally restricted 3C' , 3C Expression in endocardium covering atrioventricular endocardial cushions.

Specimen 3D,D': embryonic day 9.5; Sox7tm1.1Dsco/Sox7tm1.1Dsco (more )
Structure Level Pattern Image Note
TS15: atrioventricular canal endocardial lining Weak 3D' , 3D Expression in atrioventricular endocardium reduced compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory