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Gene Expression Data
Assay Details
Assay
Reference: J:163272 Haugas M, et al., Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space. Dev Dyn. 2010 Sep;239(9):2452-69
Assay type: RNA in situ
MGI Accession ID: MGI:7516495
Gene symbol: Gata2
Gene name: GATA binding protein 2
Probe: Gata2 probe
Probe preparation: Antisense labelled with radioactivity RNA
Results
Specimen 3G control: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vestibular component epithelium Present Regionally restricted 3G Expression is in the nonsensory epithelium.
TS22: vestibular component mesenchyme Present Regionally restricted 3G Expression is in mesenchymal cells next to the developing vestibular structures.
Specimen 3H control: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 3H Expression is in the nonsensory epithelium.
Specimen 3K: embryonic day 14.5; Foxg1tm1(cre)Skm/Foxg1+, Gata2tm1Msal/Gata2tm1Msal (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: vestibular component epithelium Absent 3K
TS22: vestibular component mesenchyme Absent 3K
Specimen 3L: embryonic day 14.5; Foxg1tm1(cre)Skm/Foxg1+, Gata2tm1Msal/Gata2tm1Msal (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cochlea epithelium Absent 3L
Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: superior semicircular canal epithelium Strong Regionally restricted 6A Expression is in the nonsensory epithelium of the three semicircular ducts.
TS20: superior semicircular canal mesenchyme Present Regionally restricted 6A Expression is in the innermost mesenchymal cells closest to the epithelium, and is absent in regions close to or in the condensing outer mesenchyme of the prospective otic capsule.
Specimen 6B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: superior semicircular canal epithelium Strong Regionally restricted 6B Expression is in the nonsensory epithelium.
TS22: superior semicircular canal mesenchyme Strong Regionally restricted 6B Expression is in the innermost mesenchymal cells closest to the epithelium, and is absent in regions close to or in the condensing outer mesenchyme of the prospective otic capsule.
Specimen 6C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: superior semicircular canal epithelium Strong Regionally restricted 6C Expression is in the nonsensory epithelium.
TS23: superior semicircular canal mesenchyme Present Regionally restricted 6C Expression is in the innermost mesenchymal cells closest to the epithelium, and is absent in regions close to or in the condensing outer mesenchyme of the prospective otic capsule.
Specimen 6D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: superior semicircular canal epithelium Strong Regionally restricted 6D Expression is in the nonsensory epithelium.
TS26: superior semicircular canal mesenchyme Weak Regionally restricted 6D Expression is in the innermost mesenchymal cells closest to the epithelium, and is absent in regions close to or in the condensing outer mesenchyme of the prospective otic capsule.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory