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Gene Expression Data
Assay Details
Assay
Reference: J:156945 Hwang CH, et al., Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13
Assay type: RNA in situ
MGI Accession ID: MGI:7516110
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: Bmp2 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: organ of Corti Present 3E Expression did not overlap with that of Bmp4 but coincided within the sensory region of the cochlea.
Specimen 3F: embryonic day 16.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS24: organ of Corti Present 3F Similar as in the control.
Specimen 4A': embryonic day 15.5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Cell Type Level Pattern Image Note
TS23: cochlea cochlear outer hair cell Present Regionally restricted 4A' Expressed in the outer hair cell in the organ of Corti.
Specimen 4B': embryonic day 15.5; Bmp2tm1Brd/Bmp2tm1.1Mis, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cochlea Absent 4B'
Specimen 5A: embryonic day 17.5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Cell Type Level Pattern Image Note
TS25: organ of Corti cochlear outer hair cell Present 5A
Specimen 5B: embryonic day 17.5; Bmp2tm1Brd/Bmp2tm1.1Mis, Gfi1tm1(cre)Gan/Gfi1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: organ of Corti cochlear outer hair cell Absent 5B
Specimen not shown: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted Only detectable in the apical cochlear region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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