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Gene Expression Data
Assay Details
Assay
Reference: J:267238 Sun K, et al., Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology. 2009 May;49(5):1645-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7514933
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 4E: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: liver Ambiguous 4E Expression in controls not specifically detailed.
Specimen 4F: postnatal week 3; Srftm1Rmn/Srftm1Rmn, Tg(Alb1-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: liver Strong 4F Authors report a 2.4-fold increase in number of expressing cells compared to control.
Specimen 5C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Ambiguous 5C Expression in controls not specifically detailed.
Specimen 5F: postnatal adult; Srftm1Rmn/Srftm1Rmn, Tg(Alb1-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: liver Strong 5F In livers with extensive loss of Srf expression, the number of Casp3-expressing cells increased 19-fold compared with control.
Specimen 5I: postnatal adult; Srftm1Rmn/Srftm1Rmn, Tg(Alb1-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: liver Trace 5I In livers with mosaic loss of Srf expression, the number of Casp3-expressing cells increased only slightly compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory