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Gene Expression Data
Assay Details
Assay
Reference: J:317244 Lee J, et al., Fetal hematopoietic stem cells express MFG-E8 during mouse embryogenesis. Exp Mol Med. 2015 Jul 24;47:e174
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7514400
Gene symbol: Cd34
Gene name: CD34 antigen
Antibody: anti-Cd34
Detection system: Secondary antibody
Results
Specimen 1e/f/g: embryonic day 10.5 (more )
Note: Double labeled: red - Cd34; green - Mfge8 (assay MGI:7514399).
Structure Cell Type Level Pattern Image Note
TS17: blood hematopoietic stem cell Present Regionally restricted 1f , 1g , 1e Expressed in the yolk sac blood islands as aggregates.
TS17: yolk sac mesenchyme hematopoietic stem cell Present Regionally restricted 1f , 1g , 1e Expressed in the yolk sac blood islands as aggregates.
Specimen 2c/d: embryonic day 11.5 (more )
Note: Double labeled: red - Cd34; green - Mfge8 (assay MGI:7514399).
Structure Cell Type Level Pattern Image Note
TS19: blood hematopoietic stem cell Present Regionally restricted 2d , 2c Expressed in the dorsal aorta and cardinal veins region.
TS19: cardinal vein hematopoietic stem cell Present Regionally restricted 2d , 2c Expressed in the cardinal veins region.
TS19: dorsal aorta hematopoietic stem cell Present Regionally restricted 2d , 2c Expressed in the dorsal aorta region.
Specimen 2g/h: embryonic day 11.5 (more )
Note: Double labeled: red - Cd34; green - Mfge8 (assay MGI:7514399).
Structure Cell Type Level Pattern Image Note
TS19: blood hematopoietic stem cell Present Regionally restricted 2g , 2h Expressed in many prominent colonies of eosinophilic and nucleate cells over the entire fetal liver parenchyma.
TS19: liver parenchyma hematopoietic stem cell Present Regionally restricted 2g , 2h Expressed in many prominent colonies of eosinophilic and nucleate cells over the entire fetal liver parenchyma.
Specimen 3c/d: embryonic day 11.5 (more )
Note: Double labeled: red - Cd34; green - Mfge8 (assay MGI:7514399).
Structure Cell Type Level Pattern Image Note
TS19: blood hematopoietic stem cell Present Regionally restricted 3d , 3c Expressed in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme.
TS19: chorionic plate hematopoietic stem cell Present Regionally restricted 3d , 3c Expressed in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme.
TS19: labyrinthine zone hematopoietic stem cell Present Regionally restricted 3d , 3c Expressed in a number of cells with large nuclei in large fetal blood vessels in the chorioallantoic mesenchyme.
Specimen S2 yolk sac: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: blood hematopoietic stem cell Present S2_yolk sac
TS19: yolk sac hematopoietic stem cell Present S2_yolk sac
Specimen S2 aorta: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: blood hematopoietic stem cell Present S2_aorta
TS19: cardinal vein hematopoietic stem cell Present S2_aorta
TS19: dorsal aorta hematopoietic stem cell Present S2_aorta
Specimen S2 placenta: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: labyrinthine zone hematopoietic stem cell Present S2_placenta
Specimen S2 liver: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: liver parenchyma hematopoietic stem cell Present S2_liver Expressed in many prominent colonies of eosinophilic and nucleate cells over the entire fetal liver parenchyma.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory