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Gene Expression Data
Assay Details
Assay
Reference: J:338018 Stathopoulou A, et al., CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression. Cardiovasc Res. 2023 Apr 13;
Assay type: RNA in situ
MGI Accession ID: MGI:7512999
Gene symbol: Hand1
Gene name: heart and neural crest derivatives expressed 1
Results
Specimen S4C,C': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present S4C' , S4C

Specimen S4C'': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present S4C''

Specimen S4D,D': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: outflow tract Weak S4D' , S4D Expression significantly reduced, especially in outflow tract

Specimen S4D'': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: outflow tract Weak S4D'' Expression significantly reduced, especially in outflow tract


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory