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Gene Expression Data
Assay Details
Assay
Reference: J:338018 Stathopoulou A, et al., CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression. Cardiovasc Res. 2023 Apr 13;
Assay type: RNA in situ
MGI Accession ID: MGI:7512991
Gene symbol: Mef2c
Gene name: myocyte enhancer factor 2C
Results
Specimen 3E,E': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present 3E' , 3E
TS15: secondary heart field Present 3E' , 3E
Specimen 3E'': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Present 3E''
Specimen 3E''': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pericardium Present Regionally restricted 3E''' Expression in dorsal pericardial wall.
Specimen 3F,F': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: branchial arch Present 3F' , 3F
TS15: secondary heart field Weak 3F , 3F' Reduced expression throughout second heart field.
Specimen 3F'': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: heart Present 3F''
Specimen 3F''': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: pericardium Ambiguous 3F''' Expression in dorsal pericardial wall not described.
Specimen S3C,C': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: secondary heart field Present S3C , S3C'
Specimen S3C'',C''': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pericardium Present Regionally restricted S3C'' , S3C''' dorsal
Specimen S3D,D': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: secondary heart field Weak S3D , S3D' Reduced expression throughout second heart field.
Specimen S3D'',D''': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: pericardium Ambiguous S3D''' , S3D'' Expression in dorsal pericardial wall not described.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory