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Gene Expression Data
Assay Details
Assay
Reference: J:338018 Stathopoulou A, et al., CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression. Cardiovasc Res. 2023 Apr 13;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7512985
Gene symbol: Tbx5
Gene name: T-box 5
Results
Specimen S6 Tbx5 Control: embryonic day 9.5 (more )
Note: Double labeled: green - Tbx5; red - Tbx1 (assay MGI:7512984).
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted S6_Control TBX5 , S6_Control (merged) Expression at venous pole.
Specimen S6 Tbx5 cKO: embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant. Double labeled: green - Tbx5; red - Tbx1 (assay MGI:7512984).
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted S6_cKO TBX5 , S6_cKO (merged) Authors report normal boundary between Tbx5- and Tbx1-expressing cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory