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Gene Expression Data
Assay Details
Assay
Reference: J:337240 Huang X, et al., Generation and characterization of a Myh6-driven Cre knockin mouse line. Transgenic Res. 2021 Dec;30(6):821-835
Assay type: Recombinase reporter
MGI Accession ID: MGI:7511474
Gene symbol: A1cf
Gene name: APOBEC1 complementation factor
Reporter: tdTomato
Antibody: anti-tdTomato (600-401-379)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: tamoxifen (0.2 mg/g of body weight) was administered at P8W and samples analyzed 48 hours later
Results
Specimen Fig4(g) TNNI3: postnatal week 8; A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: cardiac muscle tissue cardiac muscle myoblast Present 4(g) TNNI3 overlaps with anti-TNNI3 immunopositive cell
Specimen Fig4(g) PDGFRa: postnatal week 8; A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: heart fibroblast of cardiac tissue Absent 4(g) PDGFRa not in anti-PDFGRa immunopositive cardiac fibroblast cells
Specimen Fig4(g) PDGFRb: postnatal week 8; A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: heart cardiac endothelial cell Absent 4(g) PDGFRb not in anti-CDH5 immunopositive endothelial cells; not in anti-PDGFRb immunopositive coronary vascular pericyte
TS28: heart pericyte Absent 4(g) PDGFRb not in anti-CDH5 immunopositive endothelial cells; not in anti-PDGFRb immunopositive coronary vascular pericyte
Specimen Fig4(g) aSMA: postnatal week 8; A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: coronary artery blood vessel smooth muscle cell Absent 4(g) aSMA not in anti-aSMA immunopositive smooth muscle cells
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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