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Gene Expression Data
Assay Details
Assay
Reference: J:127123 Barker N, et al., Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007 Oct 25;449(7165):1003-7
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7510179
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Reporter: lacZ
Direct Detection
Results
Specimen 3b/c: postnatal adult; Lgr5tm1Ah/Lgr5+ (more )
Note: Section fixed in 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 3c , 3b Expression is restricted to the 6-8 slender cells sandwiched between the Paneth cells at the crypt base.
Specimen 3d/e: postnatal adult; Lgr5tm1Ah/Lgr5+ (more )
Note: Section fixed in 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: large intestine crypt of lieberkuhn Present Regionally restricted 3d , 3e In the colon, expression is confined to a few cells located at the crypt base.
Specimen 3f/g: postnatal adult; Lgr5tm1Ah/Lgr5+ (more )
Note: Section fixed in 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: stomach glandular epithelium Present Regionally restricted 3f , 3g Expression is limited to the base of the glands.
Specimen Not shown: postnatal adult; Lgr5tm1Ah/Lgr5+ (more )
Note: Section fixed in 1% formaldehyde, 0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS28: brain Present Single cells
TS28: eye Present Single cells
TS28: hair follicle Present Single cells
TS28: mammary gland Present Single cells
TS28: reproductive organ Present Single cells
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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